Multi-strut ablation and sensing catheter devices and methods

Inventors

Turovskiy, Roman • KIRKLAND, David R. • Danitz, David J. • MOOSAVI, David • QUINTOS, Rodel • Bradway, Ryan C. • Denison, Andy E. • Montgomery, Dylan R. • D'Aquanni, Peter J.

Assignees

Pulse Biosciences Inc

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Publication Number

US-12564440-B2

Patent

Publication Date

2026-03-03

Expiration Date


Abstract

Methods and apparatuses are disclosed for providing pulsed electrical treatment (including high voltage, sub-microsecond pulsed electric energy) to tissue, including cardiac tissue. The apparatus may include deployable electrodes that conform to transitional surfaces. These apparatuses may include single or multiple tiers of wire loops forming petal-like electrodes.

Core Innovation

The disclosure describes catheter-based pulsed-electric-field ablation apparatuses comprising an elongate body and deployable angled arms carrying treatment electrodes and mapping or sensing electrodes. In one configuration, a first treatment electrode and a second treatment electrode extend between and connect to a shared plurality of arms, with the second treatment electrode positioned radially outward of the first treatment electrode in the deployed state.

In another configuration, first and second pluralities of arms carry treatment electrodes separated along the longitudinal axis of the elongate body alongside mapping or sensing electrodes. Disclosed embodiments include expandable catheter electrode assemblies, wire-frame, mesh, loop, and deployable-arm configurations, as well as systems linking a mapping subsystem with nanosecond pulsed-energy delivery. These devices conform to variable lumen anatomy to deliver circumferential or targeted tissue treatment across cardiac ablation and other tissue applications.

Claims Coverage

The claim coverage includes two inventive features directed to pulsed-electric-field delivery apparatuses configured with deployable angled arms.

Radially outward treatment electrodes on a shared arm set

An elongate body and a plurality of arms configured to extend from the elongate body at an angle in a deployed state, with a first treatment electrode and a second treatment electrode extending between and connecting to the plurality of arms such that the second treatment electrode is radially outward of the first treatment electrode, and one or more mapping and/or sensing electrodes on the arms.

Longitudinally separated treatment electrodes on separate arm sets

An elongate body comprising a first plurality of arms and a second plurality of arms configured to extend from the elongate body at an angle in a deployed state, with a first treatment electrode extending between and connecting to the first plurality of arms, a second treatment electrode extending between and connecting to the second plurality of arms separated along a longitudinal axis of the elongate body, and one or more mapping and/or sensing electrodes.

The claims cover pulsed-electric-field apparatuses providing either radially outward treatment electrodes on a shared set of deployable arms or longitudinally separated treatment electrodes across two sets of deployable arms, with mapping and/or sensing electrodes included in each arrangement.

Stated Advantages

The devices are designed to conform to variable lumen anatomy.

The devices deliver circumferential or targeted tissue treatment.

Documented Applications

Cardiac tissue treatment and cardiac ablation, including pulmonary-vein isolation.

Other tissue applications.

Catheter electrode assemblies and arrays configured for treatment-area identification, electrode contact confirmation, pulsed electrical treatment of tissue, and withdrawal.

A system linking a mapping subsystem with nanosecond pulsed-energy delivery.

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