Drug delivery device including reservoir with flexible lining
Inventors
Assignees
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Publication Number
US-12558477-B2
Publication Date
2026-02-24
Expiration Date
Abstract
Embodiments of the present disclosure relate to techniques, processes, devices or systems for pump devices for providing a fixed volume of fluid, which is delivered and refilled within one pumping cycle. In one approach, a wearable drug delivery device may include a reservoir configured to store a liquid drug, and a drive mechanism coupled to the reservoir for receiving the liquid drug. The drive mechanism may include a housing defining a chamber, the housing including an inlet valve operable to receive the liquid drug and an outlet valve operable to expel the liquid drug from the chamber, and a resilient sealing member within the chamber. The drive mechanism may further include a shape memory wire coupled to the resilient sealing member, wherein the shape memory wire is operable to bias the resilient sealing member within the chamber.
Core Innovation
The invention relates to a reservoir of a wearable drug delivery device having a housing that defines an interior cavity and includes an inlet and an outlet communicating with the reservoir through a septum having an end surface with an opening. A flexible liner is positioned within the interior cavity and is operable to transition between an expanded configuration and a collapsed configuration in response to medicament entering a liquid chamber of the reservoir.
In the expanded configuration, the flexible liner is in a natural expanded state and flush with the end surface of the septum that has the opening before a medicament passes into the liquid chamber. In the collapsed configuration, the flexible liner buckles, collapses, or folds under the medicament to decrease a volume of the flexible liner as more medicament enters the liquid chamber, which is defined by an exterior of the flexible liner and the interior surface of the housing.
The described reservoir architecture further includes fill port chamber features and septum and vent structures for receiving medicament through a fill needle inlet. The medicament passes through a pressure-activated septum having a slit, and an air vent with a hydrophobic cover is associated with the fill port chamber. Outlet features include an outlet cavity positioned in the housing interior surface and a polymer mesh membrane positioned inside the outlet cavity, to manage air bubbles during delivery.
Claims Coverage
The partial content provides one independent claim, with multiple dependent claims refining the reservoir architecture. The core inventive coverage centers on the flexible liner transitioning between expanded and collapsed configurations to define a liquid chamber, together with septum and vent fill features and outlet bubble-management structures.
Flexible liner expanded-to-collapsed liquid chamber definition
A housing defining an interior cavity with an inlet and an outlet that communicate with the reservoir through a septum having an end surface with an opening, and a flexible liner within the interior cavity operable to transition between an expanded configuration and a collapsed configuration in response to medicament entering a liquid chamber, wherein the liquid chamber is defined by an exterior of the flexible liner and the interior surface of the housing.
Fill port chamber with fill needle inlet and air vent
The reservoir further comprises a fill port chamber that encloses the housing inlet and includes a fill needle inlet and an air vent.
Self-sealing septum and hydrophobic cover for fill needle inlet and air vent
The reservoir further includes a self-sealing septum over the fill needle inlet and a hydrophobic cover over the air vent.
Pressure-activated septum with slit fluidly connecting chambers
The reservoir adds a pressure-activated septum with a slit to fluidly connect a liquid chamber and a fill port chamber when coupled to the fill port chamber and the housing.
Outlet cavity with polymer mesh membrane
The reservoir describes an outlet having an outlet cavity recessed in the housing interior surface, with a polymer mesh membrane positioned inside that outlet cavity.
Across the provided claims, the inventive coverage is focused on a flexible liner reservoir in which a flexible liner transitions between expanded and collapsed configurations as medicament enters a liquid chamber defined by the exterior of the flexible liner and the interior surface of the housing, with dependent refinements for fill-port septum and vent features and an outlet cavity having a polymer mesh membrane.
Stated Advantages
Reduces a volume of the flexible liner as more medicament enters the liquid chamber.
Enables medicament to pass into the liquid chamber after the flexible liner is flush with the septum opening before entry.
Includes an outlet polymer mesh membrane to manage air bubbles during delivery.
Documented Applications
Wearable drug delivery device reservoir architecture for receiving and delivering medicament, including reservoir liquid chamber operation with fill port chamber and outlet features.
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