System and method for adjusting insulin delivery

Inventors

Mazlish, Bryan • Desborough, Lane • Naylor, Ross

Assignees

Insulet Corp

Abstract

The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Such personalization may include adjusting user specific dosage parameters in response to one or more back-filled time segments associated with a diurnal time block.

Core Innovation

Insulin management is performed by receiving a user input comprising a total daily dose of insulin and patient weight, and generating an insulin delivery profile based on the user input including the total daily dose of insulin and the patient weight. Insulin is delivered based on the insulin delivery profile and responsive to glucose values received. Sets of one or more glucose target values are determined based on the glucose values received and the user input including the total daily dose of insulin and the patient weight.

Variations of predicted glucose values are determined from the multiple sets of one or more glucose target values. An evaluation of the variations of predicted glucose values is performed, and a set of one or more glucose target values is selected from the multiple sets based on the evaluation. The insulin delivery profile is adjusted based on the set of one or more glucose target values selected.

Insulin delivery is then performed based on the adjusted insulin delivery profile. In the dependent aspects, variations of predicted glucose values are determined by using predicted future glucose values at various points in time, and the evaluation uses a cost function measuring differences between predicted future glucose values and the multiple sets of one or more glucose target values. A set of one or more glucose target values is selected based on minimizing a cost function, and the insulin delivery profile is further adjusted based on detected time periods when basal delivery differs from a baseline delivery rate.

Claims Coverage

The independent claims are directed to methods and systems that generate and adjust an insulin delivery profile using multiple candidate sets of glucose target values, where predicted glucose variations are evaluated and a target set is selected based on the evaluation. A total of 2 independent claims are present in the provided claim set, with the same core inventive workflow represented in both.

Both independent claims cover delivering insulin by generating an insulin delivery profile from user input (total daily dose of insulin and patient weight), predicting glucose variations under multiple sets of glucose target values, evaluating those variations, selecting a target set from the multiple sets based on the evaluation, and adjusting the insulin delivery profile accordingly before delivering insulin again.

Stated Advantages

Documented Applications

No documented applications found