Protective barrier compositions, and uses thereof
Inventors
Monsul, Nicholas T. • Berkes, Eva A. • BOEHM, Frederick T.
Assignees
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Publication Number
US-12495800-B2
Publication Date
2025-12-16
Expiration Date
Abstract
The subject invention provides compositions and methods of enhancing the barrier function of surfaces and/or objects using biochemical-producing microbes and/or byproducts synthesized by the microbes. Preferred embodiments of the invention provide compositions, and the methods of using the same, comprising a Lactobacillus sp., and/or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.
Core Innovation
The invention relates to protective barrier compositions and use of a surface treatment that enhances a barrier against contamination. A composition is applied to a surface, and the surface becomes less susceptible to microbial, viral and/or chemical contamination. The composition comprises inactivated Lactobacillus spp. that had been grown as biofilm, and specifically uses Lactobacillus fermentum Qi6 having Accession No. PTA-122195.
The treated barrier is applied to surfaces on objects selected from medical instruments, countertops, protective suits, tables, appliances, chairs, dishes, utensils, medical implants, bandages, personal hygiene products, clothing, eyewear, footwear, headwear, masks, vehicles, boats, ships, cars, trucks, tanks, airplanes and trains. The approach emphasizes that applying the specified inactivated, biofilm-grown Lactobacillus composition enhances the barrier such that contamination susceptibility is reduced.
The disclosed invention further includes a method for enhancing a barrier against chemical, viral and/or microbial contamination of a surface. The method comprises applying the same type of composition containing inactivated Lactobacillus spp. grown as a biofilm, so that when applied, the surface becomes less susceptible to microbial, viral and/or chemical contamination.
Claims Coverage
The partial document provides two independent claims: clm-00001 (a treated surface) and clm-00010 (a method for enhancing a barrier). Across these claims, the core inventive concept is the application of a composition containing inactivated Lactobacillus fermentum Qi6 (Accession No. PTA-122195) that had been grown as a biofilm, wherein application makes the surface less susceptible to microbial, viral and/or chemical contamination.
Inactivated biofilm-grown Lactobacillus fermentum Qi6 protective barrier surface treatment
A surface having applied thereto a composition comprising inactivated Lactobacillus spp. that had been grown as biofilm, wherein the composition enhances a barrier such that, when the composition is applied to the surface, the surface becomes less susceptible to microbial, viral and/or chemical contamination, and wherein the bacterial strain is L. fermentum Qi6 having Accession No. PTA-122195.
Applying inactivated biofilm-grown Lactobacillus fermentum Qi6 to enhance a barrier against contamination
A method for enhancing a barrier against chemical, viral and/or microbial contamination of a surface, wherein the method comprises applying to the surface a composition comprising inactivated Lactobacillus spp. that had been grown as a biofilm, wherein when the composition is applied to the surface, the surface becomes less susceptible to microbial, viral and/or chemical contamination, and wherein the bacterial strain is L. fermentum Qi6 having Accession No. PTA-122195.
Both independent claims cover the same central inventive approach: applying a composition comprising inactivated Lactobacillus fermentum Qi6 (Accession No. PTA-122195) that had been grown as biofilm to enhance a barrier so that a surface becomes less susceptible to microbial, viral and/or chemical contamination. Claim clm-00001 focuses on a surface on specified object types, while claim clm-00010 focuses on performing the method on such surfaces.
Stated Advantages
The composition enhances a barrier so the surface becomes less susceptible to microbial, viral and/or chemical contamination.
Documented Applications
The treated surface is on objects selected from medical instruments, countertops, protective suits, tables, appliances, chairs, dishes, utensils, medical implants, bandages, personal hygiene products, clothing, eyewear, footwear, headwear, masks, vehicles, boats, ships, cars, trucks, tanks, airplanes and trains.
The method enhances a barrier against chemical, viral and/or microbial contamination of a surface, including surfaces chosen from skin, intestine, stomach, lung, eye, mouth, nose, ear, trachea, vagina, or esophagus of a subject.
The method applies to a surface provided on objects selected from medical and consumer contact surfaces and items, including medical instruments, countertops, protective suits, tables, appliances, chairs, dishes, utensils, medical implants, personal hygiene products, bandages, clothing, eyewear, footwear, headwear, and masks.
The method applies to surfaces on objects selected from vehicles, boats, ships, cars, trucks, tanks, airplanes, and trains.
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