Method and device for treating eye disease

Inventors

Jiang, Rui Jing • Kao, Brandon Wei-Hsiang

Assignees

Avisi Technologies Inc

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Publication Number

US-12472096-B2

Patent

Publication Date

2025-11-18

Expiration Date


Abstract

Described herein are devices used to treat high intraocular pressure and glaucoma. An example device includes a plate comprising a first surface opposite a second surface. The first surface includes a series of fluid channels. The device also includes a first coating on the first surface and a second coating on the second surface. The device is configured to lower intraocular pressure by draining aqueous humor from an anterior chamber to subconjunctival space of a patient's eye.

Core Innovation

The invention is directed to a device for lowering intraocular pressure that includes a plate having a first end and a second end, with a first surface opposite a second surface. The first surface includes a series of fluid channels configured in an intersecting grid pattern and extending from the first end to the second end of the plate. The first end is configured for insertion into an anterior chamber of an eye, and the second end is configured for insertion into a subconjunctival space of the eye.

The device includes a first coating on the first surface that conforms to a topography of the series of fluid channels, and a second coating on the second surface. The series of fluid channels is configured as an intersecting grid pattern and may be characterized as an interconnected network of open-ended channels forming intersecting fluid pathways. This plate and channel arrangement is configured to establish fluid flow from the anterior chamber toward the subconjunctival space.

The invention is also directed to a method of reducing intraocular pressure by injecting the device into an eye with high intraocular pressure. The injected device includes the plate with the intersecting grid pattern of series of fluid channels, with the first end configured for insertion into the anterior chamber and the second end configured for insertion into the subconjunctival space. After injection, treating the high intraocular pressure is carried out using the device having the topography-conforming first coating and the second coating on the second surface.

Claims Coverage

The partial content provides two independent claims, covering both a device and a method. Across the two independent claims, the inventive features consistently focus on a plate with an intersecting grid pattern of fluid channels extending between anterior chamber and subconjunctival space, and coatings including a topography-conforming first coating on the channel-bearing surface, plus a second coating on the opposite surface.

Plate with intersecting grid pattern of fluid channels between anterior chamber and subconjunctival space

A plate having a first end and a second end, the plate comprising a first surface opposite a second surface, wherein the first surface includes a series of fluid channels configured in an intersecting grid pattern extending from the first end to the second end of the plate, the first end configured for insertion into an anterior chamber of an eye, and the second end configured for insertion into a subconjunctival space of the eye.

Topography-conforming first coating and second coating on opposite plate surfaces

A first coating on the first surface that conforms to a topography of the series of fluid channels and a second coating on the second surface.

Injecting the device into an eye with high intraocular pressure and treating the high intraocular pressure

Injecting a device into an eye with high intraocular pressure, the device including a plate with the first end and second end, the series of fluid channels in an intersecting grid pattern extending from the first end to the second end of the plate, the first end configured for insertion into an anterior chamber of the eye, and the second end configured for insertion into a subconjunctival space of the eye, the plate further comprising a first coating on the first surface that conforms to a topography of the series of fluid channels and a second coating on the second surface; and treating the high intraocular pressure.

The provided independent claims cover a plate-based IOP-lowering device in which a first surface includes an intersecting grid pattern of series of fluid channels extending from an anterior chamber insertion end to a subconjunctival space insertion end, together with coatings including a first coating conforming to channel topography and a second coating on the opposite surface. The method claim uses injecting this same device into an eye with high intraocular pressure followed by treating the high intraocular pressure.

Stated Advantages

Not explicitly described in patent.

Documented Applications

Not explicitly described in patent.

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