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Publication Number
US-12454671-B2
Publication Date
2025-10-28
Expiration Date
Abstract
This disclosure describes an improved heat transfer system for use in reaction vessels used in chemical and biological processes. In one embodiment, a heat transfer baffle comprising two sub-assemblies adjoined to one another is provided.
Core Innovation
The invention describes a heat-transfer baffle for a reactor vessel used to carry out a chemical, pharmaceutical, or biological process. The baffle has at least one relief channel and at least one distribution channel formed between a first material and a support material. The distribution channel contains heat-transfer fluid, and the baffle attaches to the vessel at a substantially seamless attachment point.
The described baffle may use back-to-back subassemblies, with relief channels that reinforce the baffle and can vent leakage. Headers distribute heat-transfer fluid, and optional compartments permit independent circulation. The supplied partial content does not include the background section, so it does not explicitly state the problem being solved there.
Claims Coverage
The supplied relevant claims identify one independent claim with one inventive feature directed to carrying out a chemical, pharmaceutical, or biological process in a reactor vessel using a heat-transfer baffle with specified channels and vessel attachment.
Heat-transfer baffle with fluid-containing distribution channel
Claim 1 covers a method for carrying out a chemical, pharmaceutical, or biological process within a reactor vessel. The reactor vessel comprises a heat-transfer baffle with at least one relief channel and at least one distribution channel formed between a first material and a support material; the distribution channel contains heat-transfer fluid, and the baffle is attached to the vessel at a substantially seamless attachment point.
The independent claim centers on using a reactor-vessel baffle that combines a relief channel, a heat-transfer-fluid distribution channel, and a substantially seamless attachment point.
Stated Advantages
The relief-channel structure reinforces the baffle and can vent leakage.
The substantially seamless vessel attachment supports sanitary cleaning.
Reported cooling tests demonstrate an overall heat-transfer coefficient [procedural detail omitted for safety].
Documented Applications
The baffle is used in a reactor vessel for carrying out a chemical process, a pharmaceutical process, or a biological process.
The biological processes identified include microbiological culture, mammalian cell culture, and plant cell culture.
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