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Publication Number
US-12440620-B2
Publication Date
2025-10-14
Expiration Date
Abstract
A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.
Core Innovation
A wearable/disposable fluid delivery device is described for delivering medicament to a patient via a delivery path while the device includes a sealed fluid reservoir proximate a proximal end with a sliding seal piston. The sealed reservoir contains the medicament, and the delivery path fluidly couples the fluid reservoir and the patient wearing the fluid delivery device. The sliding seal piston moves in a distal direction to force medicament through the delivery path.
The device uses a basal actuator and a bolus actuator to drive the sliding seal piston for both basal and bolus delivery. The basal actuator includes a basal element slidingly coupled to an inside surface of a hydraulic fluid reservoir containing a hydraulic fluid, and the hydraulic fluid reservoir is fluidly coupled to a hydraulic fluid passage. The basal actuator forces a sliding seal element in a distal direction to force hydraulic fluid to flow out of the hydraulic fluid reservoir through the hydraulic fluid passage, moving the sliding seal piston at a controlled basal rate.
The bolus actuator is directly coupled to a proximal end of the basal actuator and is configured to directly or indirectly move the sliding seal piston a discrete bolus amount at a time. Multiple basal actuator implementations are outlined, including electrochemical basal expansion pushing a piston and plunger, and a hydraulically actuated basal engine using an aperture-based flow restriction whose rate depends on pressure/energy source, hydraulic viscosity, and aperture/friction. The hydraulic fluid passage can include a U-shaped hydraulic passage and passage geometries having non-constant cross-section and optionally non-straight, non-constant passages for compactness and manufacturability.
Claims Coverage
Independent claim clm-00001 defines two main inventive feature groups: a sealed medicament reservoir with a sliding seal piston coupled to a patient delivery path, and a basal actuator using a hydraulic fluid reservoir and hydraulic fluid passage to move the sliding seal piston at a controlled basal rate, coordinated with a bolus actuator directly coupled to the basal actuator to move the sliding seal piston a discrete bolus amount at a time.
Sealed medicament reservoir with sliding seal piston and patient delivery path
A fluid reservoir configured to contain medicament, sealed proximate a proximal end with a sliding seal piston, and a delivery path configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device.
Hydraulic fluid passage coupled to reservoir
A hydraulic fluid passage having a proximal end and a distal end, the distal end coupled to the proximal end of the fluid reservoir.
Basal actuator forcing hydraulic fluid flow to move sliding seal piston at controlled basal rate
A basal actuator including a basal element slidingly coupled to an inside surface of a hydraulic fluid reservoir containing a hydraulic fluid, the hydraulic fluid reservoir fluidly coupled to the proximal end of the hydraulic fluid passage, configured to force a sliding seal element in a distal direction to force the hydraulic fluid to flow out of the hydraulic fluid reservoir through the hydraulic fluid passage moving the sliding seal piston at a controlled basal rate.
Bolus actuator directly coupled to basal actuator for discrete bolus amounts
A bolus actuator directly coupled to a proximal end of the basal actuator, configured to directly or indirectly move the sliding seal piston a discrete bolus amount at a time.
Bolus actuator with plunger depression and pawl
The bolus actuator includes a plunger configured to depress and move a sliding seal element to deliver a discrete bolus amount at a time, and a pawl that prevents backward motion of the plunger.
U-shaped hydraulic fluid passage
The hydraulic fluid passage is U-shaped such that the basal actuator is substantially parallel with the fluid reservoir.
The claim set centers on a sealed medicament reservoir with a sliding seal piston, driven by a basal actuator that uses hydraulic fluid reservoir/passage coupling to move the piston at a controlled basal rate, coordinated with a bolus actuator directly coupled to the basal actuator to move the sliding seal piston by discrete bolus amounts, with dependent refinements specifying bolus-actuator mechanics and hydraulic passage geometry.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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