Prosthetic heart valves

Inventors

Anderson, Rachel Jean • Schneider, Lucas Tradd • Askegaard, Gunnar Paul • Oliver, Daniel • Iyer, Ramji

Assignees

Laplace Interventional Inc

Abstract

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valves are implanted using catheter-based deployment systems that include multiple control wires. In particular implementations, the deployment systems can include a retrieval catheter that can be used to recapture the prosthetic heart valve back into a delivery sheath after being expressed from the delivery sheath. The prosthetic heart valves can include a plurality of optional suture knots to enhance migration resistance. Some delivery catheter systems can include a controllably bendable control catheter and/or a deflectable catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

Core Innovation

The invention relates to a prosthetic heart valve comprising a main body having a stent frame comprised of elongate members and a covering material on an exterior of the stent frame. The main body defines a central axis extending between an inflow end portion and an outflow end portion, and a plurality of sutures attaches the covering material to the elongate members, with suture knots protruding from an external surface of the main body along and in alignment with outer surfaces of the elongate members.

The prosthetic heart valve further includes one or more anterior flaps extending from the outflow end portion in a direction transverse to the central axis. The one or more anterior flaps comprises a septal anterior flap and a lateral anterior flap, where an edge portion of the septal anterior flap comprises a septal anterior strut framework and an edge portion of the lateral anterior flap comprises a lateral anterior strut framework.

The catheter-based transcatheter prosthetic heart valve system is for tricuspid replacement and includes a valve frame with an occluder and anterior flaps extending transverse to a central axis, including septal and lateral anterior flaps. The system can include exterior suture knots for migration resistance, and anchoring features such as posterior and anterior arms and leaflet engagement members.

The deployment system includes multiple catheters controlled to sequentially deploy and optionally retrieve the prosthetic valve, including a retrieval catheter with a self-expanding conical or funnel-shaped retrieval member and a snare loop. The deployment and retrieval applicability is described via superior vena cava and inferior vena cava approaches, including a transjugular approach, with recapturing of the valve into an outer sheath using the funnel-shaped conical retrieval member and the snare loop.

Claims Coverage

The independent claim includes 5 main inventive features: a covered stent-frame main body with a central axis, sutures with external suture knots, anterior flaps transverse to the central axis, separate septal and lateral anterior flaps with respective strut frameworks, and a septal anterior strut framework comprising S-shaped struts.

Across the provided claim coverage, the core independent claim centers on a covered stent-frame prosthetic valve with transverse outflow anterior flaps and a septal anterior strut framework defined by S-shaped struts. The remaining features refine the placement of suture knots and distinguish septal and lateral anterior flap structures.

Stated Advantages

Documented Applications