Online fluid generating peritoneal dialysis cycler
Inventors
Jeyachandran, Ramkumar • Wellings, Anders J.
Assignees
Vantive Health GmbH • Baxter Innovation & Business Solutions Private Ltd • Vantive US Healthcare LLC
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Publication Number
US-12433983-B2
Publication Date
2025-10-07
Expiration Date
Abstract
A peritoneal dialysis (“PD”) machine includes a water pump; a concentrate pump; a water valve, and an inlet to the water valve positioned to receive purified water; a concentrate valve, and an inlet to the concentrate valve positioned to receive PD fluid concentrate; a mixing line located downstream from the water pump and the a concentrate pump; a conductivity sensor positioned to sense mixed purified water and PD fluid concentrate that form fresh PD fluid; a flexible patient line configured to bring fresh PD fluid to and remove used PD fluid from a patient; and a control unit configured to control the water pump, the concentrate pump, the water valve and the concentrate valve, to receive an output from the conductivity sensor, and to run a disinfection sequence in which (i) the inlet to the concentrate valve alternatively receives disinfectant or (ii) the flexible patient line alternatively receives disinfectant.
Core Innovation
The invention relates to a peritoneal dialysis machine for automated peritoneal dialysis that produces fresh PD fluid by mixing purified water with one or more PD fluid concentrate sources using a water pump and a concentrate pump, together with a water valve and a concentrate valve positioned to receive purified water and PD fluid concentrate. The machine includes a mixing line downstream from the water pump and the concentrate pump, and an inline conductivity sensor positioned to sense a mixture of purified water and the PD fluid concentrate that at least partially forms fresh PD fluid.
The PD machine further includes a flexible patient line configured to bring the at least partially formed fresh PD fluid to a patient and remove used PD fluid from the patient. A control unit controls the water pump, the concentrate pump, the water valve and the concentrate valve, receives an output from the conductivity sensor, and coordinates delivery and removal using sensor feedback as described in dependent claims, including flow-related sensing and ultrafiltration determination.
A further aspect of the invention is the disinfection sequence, in which an end of the flexible patient line is directly connected to an external container of a disinfectant concentrate to receive disinfectant instead of being connected to the patient. Dependent aspects refine the disinfection sequence by routing disinfectant and/or using heating and additional sensors and fluid handling components to manage disinfectant and post-treatment rinsing and purging.
Claims Coverage
The provided content identifies one independent claim. Its claim set covers a PD machine that mixes purified water with PD fluid concentrate to form fresh PD fluid under conductivity sensing, delivers the fresh PD fluid to a patient via a flexible patient line while removing used PD fluid, and performs disinfection by directly connecting the flexible patient line end to an external container of disinfectant concentrate rather than to the patient.
Conductivity-sensed fresh PD fluid mixing from purified water and concentrate
A water pump and a concentrate pump with a mixing line downstream from the water pump and the concentrate pump, and a conductivity sensor positioned to sense a mixture of the purified water and the PD fluid concentrate that at least partially forms fresh PD fluid.
Flexible patient line for fresh PD delivery and used PD removal
A flexible patient line configured to bring the at least partially formed fresh PD fluid to a patient and remove used PD fluid from the patient.
Control of mixing valves and pumps using conductivity sensor output
A control unit configured to control the water pump, the concentrate pump, the water valve and the concentrate valve, and to receive an output from the conductivity sensor.
Disinfection sequence by directly connecting to external disinfectant concentrate container
Running a disinfection sequence in which an end of the flexible patient line is directly connected to an external container of a disinfectant concentrate to receive disinfectant instead of being connected to the patient.
Overall claim coverage centers on producing fresh PD fluid by purified water and concentrate mixing with conductivity sensing, delivering it via a flexible patient line while removing used PD fluid, and performing disinfection by direct connection of the patient-line end to an external disinfectant concentrate container rather than the patient.
Stated Advantages
Reduced disposable waste/cost.
Precise volumetric/pressure control.
Flexible use of reusable components with periodic replacement.
Documented Applications
Automated peritoneal dialysis using an online fluid-generating PD cycler that mixes purified water with PD fluid concentrate sources and delivers fresh PD fluid to a patient via a flexible patient line.
Post-treatment disinfection of the PD fluid path using a disinfection sequence with an external disinfectant concentrate container connected to the end of the flexible patient line.
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