Interested in licensing this patent?
MTEC can help explore whether this patent might be available for licensing for your application.
Publication Number
US-12419306-B2
Publication Date
2025-09-23
Expiration Date
Abstract
A Mesostigmata mite control composition comprising, as active ingredients: a specific quinoline derivative compound such as 8-fluoro-2,3-dimethyl-6-(1,1-dimethylethyl)-4-(methylcarbonyl)oxyquinoline; and at least one of other pest control agents exhibits an excellent control effect on Mesostigmata mites.
Core Innovation
The disclosed invention relates to controlling Mesostigmata mites using a composition and a combination product that include quinoline derivative compounds represented by a general formula (1) and an additional pest control agent, specifically flupyrimin and acid addition salts thereof. The targeted application includes at least one selected from the group consisting of Mesostigmata mites, homeotherms, insects, and habitats of Mesostigmata mites. The technical problem is framed as unmet acaricidal efficacy due to resistance, where improved mite control is needed.
The composition is defined by selecting at least one compound represented by general formula (1) and acid addition salts, wherein R1 represents —COCH3, R2 represents a fluorine atom, and R3 represents a t-butyl group. The invention further requires combining this quinoline derivative component with flupyrimin and acid addition salts, while constraining the mass ratio of the general formula (1) component to the flupyrimin component to 1:25 to 20:1. This formulation relationship is presented as part of achieving a control effect.
The disclosure reports that synergy is obtained when the quinoline derivative component is combined with other pesticides, including flupyrimin and multiple other listed acaricide/insecticide classes. Test results on red mites, including Dermanyssus gallinae, are described using Colby’s formula, showing a mixed-agent superiority over theoretical additive expectations. The document also identifies Mesostigmata mite groups, including Dermanyssidae and Macronyssidae, as targets of the control compositions.
Claims Coverage
The partial content includes two independent claims (clm-00001 and clm-00003). Both independent claims share the core inventive concept of using a composition/combination product containing a quinoline derivative of general formula (1) together with flupyrimin, with a constrained mass ratio between the two active-ingredient groups.
Mesostigmata mite control composition with general formula (1) quinoline derivative and flupyrimin mass ratio
Applying to at least one selected from Mesostigmata mites, homeotherms, insects, and habitats of Mesostigmata mites a composition having, as active ingredients, at least one compound represented by general formula (1) and acid addition salts thereof wherein R1 represents —COCHCH3, R2 represents a fluorine atom, and R3 represents a t-butyl group, and at least one selected from flupyrimin and acid addition salts thereof, with a mass ratio of the general formula (1) component to the flupyrimin component of 1:25 to 20:1.
Mesostigmata mite control combination product with general formula (1) quinoline derivative and flupyrimin mass ratio
Applying an effective amount to at least one selected from Mesostigmata mites, homeotherms, insects, and habitats of Mesostigmata mites of a combination product containing, as active ingredients, at least one compound represented by general formula (1) and acid addition salts thereof wherein R1 represents —COCH3, R2 represents a fluorine atom, and R3 represents a t-butyl group, and at least one selected from flupyrimin and acid addition salts thereof, with a mass ratio of the general formula (1) component to the flupyrimin component of 1:25 to 20:1.
Across the independent claims, the coverage focuses on Mesostigmata mite control compositions/combination products defined by a general formula (1) quinoline derivative component (with R1=—COCH3, R2=fluorine, R3=t-butyl) combined with flupyrimin, where the mass ratio between these two active-ingredient groups is limited to 1:25 to 20:1.
Stated Advantages
Synergistic mite control effect when combining the quinoline derivative with other pesticides, including flupyrimin, with mixed-agent superiority over theoretical additive expectations based on Colby’s formula.
Documented Applications
Control of red mites (Dermanyssus gallinae) using the described quinoline derivative and flupyrimin combination with synergism evaluated by Colby’s formula.
Control targeting Mesostigmata mite groups including Dermanyssidae and Macronyssidae, including use against selected targets selected from Mesostigmata mites, homeotherms, insects, and habitats of Mesostigmata mites.
Interested in licensing this patent?