Aberration corrections for dynamically changing media during ultrasound therapy

Inventors

Vortman, Kobi • Levy, Yoav

Assignees

Insightec Ltd

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Publication Number

US-12409345-B2

Patent

Publication Date

2025-09-09

Expiration Date


Abstract

Various approaches to delivering ultrasound energy to a target region include, prior to delivery of the ultrasound energy, populating a data structure relating multiple real-time parameter values to corresponding correction values for one or more ultrasound parameter values associated with one or more transducer elements for generating a focal zone of acoustic energy in at least the first portion of the target region; and during the treatment, (i) predicting or causing measurement of at least one of the real-time parameter values in the second portion of the target region or the non-target region; (ii) based at least in part on the predicted or measured real-time parameter value(s) and contents of the data structure, determine the correction value(s) for the ultrasound parameter value(s); and (iii) activate the transducer element(s) based at least in part on the determined correction value(s) for the ultrasound parameter value(s) so as to generate the focal zone in the second portion of the target region.

Core Innovation

The invention provides a focused-ultrasound system that uses a data structure relating real-time parameter values to correction values for an ultrasound parameter associated with a transducer element. During treatment, a controller uses a predicted or measured parameter value and the data structure to determine a correction and activate the transducer element to generate a focal zone in a portion of the target region.

The system compensates for aberrations caused by dynamically changing tissue that affect the focal zone by utilizing an autofocusing table mapping real-time parameter values to ultrasound corrections. The utilized parameters include temperature or acoustic measurements, whereas the determined corrections include phase, frequency, or power values.

Claims Coverage

The two independent claims cover a system and a method comprising two inventive features directed to delivering ultrasound energy to a target region.

System using real-time parameter values to determine ultrasound corrections

A controller populates a data structure before treatment that relates real-time parameter values to corresponding correction values for an ultrasound parameter associated with a transducer element. During treatment, the controller uses a predicted or measured value and the data structure to determine a correction and activate the element to generate a focal zone in a portion of the target region.

Method for determining and applying ultrasound corrections

The method populates a data structure before treatment to relate real-time parameter values to correction values. During treatment, it uses a predicted or measured value and the data structure to determine a correction for an ultrasound parameter, then activates a transducer element based on the correction to generate a focal zone in a portion of the target region.

The independent claims cover the system and method forms of relating real-time parameter values to ultrasound corrections to generate a focal zone in a target region during treatment.

Stated Advantages

Delivered-energy-based power control is described as supporting treatment efficacy while reducing exposure of non-target tissue.

Documented Applications

Delivering ultrasound energy to a target region during treatment, with the focal zone generated in a portion of that region.

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