Automated measurement system and method for coronary artery disease scoring
Inventors
Assignees
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Publication Number
US-12343119-B2
Publication Date
2025-07-01
Expiration Date
Abstract
An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.
Core Innovation
The invention provides an apparatus and method for coronary artery disease scoring using a computerized model representative of vascular segments of a patient. The computerized model includes one or more stenosed vascular segments and a plurality of normal vascular segments, and a processor generates an unstenosed computerized model by virtually enlarging the stenosed vascular segments based on widths of the normal vascular segments.
Using the computerized model and the unstenosed computerized model, the system determines metrics associated with vascular locations along the enlarged stenosed vascular segments. The metrics include a number of branching points, geometry information associated with individual aspects of the vascular locations, and tortuosity of the vascular locations, and the invention determines a severity for at least one stenosed vascular segment based on blood flow parameters of the computerized model and the unstenosed computerized model.
The invention converts the metrics to one or more vascular state scores, and causes a user interface to display the severity of the stenosed vascular segment and stenosis information. The disclosed scoring supports virtual revascularization by comparing blood-flow-related parameters between the imaged and unstenosed models, including special handling at bifurcations and refining modeled segments using neighbor-segment constraints and a monotonic narrowing assumption.
Claims Coverage
The document includes three independent claims (apparatus, method, and non-transitory computer storage media). Across these independent claims, the core inventive features are: generating an unstenosed computerized model by virtually enlarging stenosed segments based on normal segment widths, determining location-based metrics and using blood flow parameters to determine stenosis severity, and converting the metrics to vascular state scores used to display severity and stenosis information on a user interface.
Virtually enlarging stenosed segments to form an unstenosed computerized model
Generating an unstenosed computerized model based on virtually enlarging the plurality of stenosed vascular segments of the computerized model based on widths of the plurality of normal vascular segments.
Determining vascular-location metrics from the computerized and unstenosed models
Determining, based on the computerized model and the unstenosed computerized model, metrics associated with one or more vascular locations along the enlarged plurality of stenosed vascular segments, wherein the metrics include a number of branching points, geometry information associated with individual aspects of the vascular locations, and tortuosity of the vascular locations.
Determining stenosis severity from blood flow parameters and displaying vascular-state-score-based stenosis information
Determining, based on blood flow parameters of the computerized model and the unstenosed computerized model, a severity for at least one of the one or more stenosed vascular segments, and causing a user interface to display the severity and stenosis information, wherein the stenosis information is based on conversion of the metrics to one or more vascular state scores.
All independent claims require virtually enlarging stenosed segments to create an unstenosed computerized model, determining metrics including branching points, geometry information, and tortuosity along enlarged stenosed segments, using blood flow parameters from both models to determine severity, and converting the metrics into vascular state scores that drive display of severity and stenosis information on a user interface.
Stated Advantages
Reduced subjectivity and training time.
Real-time or near-real-time scoring during catheterization.
Documented Applications
No documented applications found
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