Systems and methods for remotely monitoring the cryogenic processing of samples

Inventors

Nancekievill, AlexanderRUTLEDGE, RUPERT

Assignees

Biosafe SA

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Publication Number

US-12320581-B2

Patent

Publication Date

2025-06-03

Expiration Date


Abstract

A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server (130) is provided, capable of transmitting freezing profile data to one or more freezers (101, . . . , 10n), transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.

Core Innovation

The invention provides a system for remotely monitoring cryogenic processing of a plurality of samples, where a plurality of thawing machines thaw the samples. A remote server located remote from the thawing machines transmits same predetermined sample thawing profile data to each thawing machine, and each thawing machine comprises at least one sensor configured to detect thawing sensor data relating to the thawing of the sample in accordance with the predetermined sample thawing profile data.

The remote server receives thawing sensor data from the thawing machines and also receives detected thawing machine data, sample thawing data and/or user data relating to thawing of the sample in accordance with the predetermined sample thawing profile data transmitted to each thawing machine. Each respective thawing machine comprises a respective control module configured to detect at least one of thawing machine data, sample thawing data and user data, and to provide a local user with means to provide a sample ID associated with the sample and select the predetermined sample thawing profile from a plurality of predetermined sample thawing profiles, wherein the predetermined sample thawing profile is associated with the sample ID.

The remote server generates a thawing consistency report from the received data that is indicative of thawing performance of the plurality of samples across the plurality of thawing machines and indicative of at least one anomaly in the received data. The remote server presents the thawing consistency report to a remote user with a graphical representation of a single thawing machine, a single user, or a single predetermined thawing profile associated with the at least one anomaly.

Claims Coverage

Independent claim clm-00001 covers remote monitoring of cryogenic processing using remote distribution of same predetermined sample thawing profile data to multiple thawing machines, collection of thawing sensor and additional data, anomaly detection via a thawing consistency report, and remote graphical presentation centered on selected perspectives. The claim includes five inventive features.

Remote server transmitting same predetermined thawing profile data

A remote server located remote from a plurality of thawing machines transmits same predetermined sample thawing profile data to each of the plurality of thawing machines.

Thawing sensor data detected in accordance with predetermined thawing profile

Each thawing machine comprises at least one sensor configured to detect thawing sensor data relating to the thawing of the sample in accordance with the predetermined sample thawing profile data.

Local control module with sample ID and profile selection associated to sample ID

Each respective thawing machine comprises a respective control module configured to detect at least one of thawing machine data, sample thawing data and user data, and to provide a local user with means to provide a sample ID associated with the sample and select the predetermined sample thawing profile from a plurality of predetermined sample thawing profiles, wherein the predetermined sample thawing profile is associated with the sample ID.

Thawing consistency report indicative of thawing performance and anomalies

The remote server receives thawing sensor data and other detected data and generates a thawing consistency report indicative of thawing performance of the plurality of samples across the plurality of thawing machines and indicative of at least one anomaly in the received data.

Graphical representation presented to remote user for a selected perspective

The thawing consistency report is presented to a remote user with a graphical representation of a single thawing machine, a single user, or a single predetermined thawing profile associated with the at least one anomaly.

The claim coverage centers on remote distribution of same predetermined sample thawing profile data, local sample ID and profile selection, remote reception of multiple data types, and generation and presentation of a thawing consistency report indicative of performance and at least one anomaly.

Stated Advantages

Provides a thawing consistency report indicative of thawing performance of the plurality of samples across the plurality of thawing machines.

Identifies at least one anomaly in the received data and presents results to a remote user.

Documented Applications

No documented applications found

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