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Publication Number
US-12305152-B2
Publication Date
2025-05-20
Expiration Date
Abstract
This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs), and particular those used for storing and/or supplying buffers and other solutions in systems for carrying out reactions in reaction vessels. In some embodiments, the DC comprises a first and second end, one or more attachment connectors at the first end, and one or more conveyance connectors at the second end. Systems comprising and methods for using and/or testing the same are also disclosed.
Core Innovation
The disclosed system horizontally deploys a disposable container positioned on an inner surface of a holder. Attachment connectors secure one end of the container to receiving connectors in the holder's front section, while conveyance connectors at the opposite end connect to a conveyance means. Engagement of that means moves the container from an undeployed configuration to a deployed configuration, extending it horizontally along the holder's interior surface.
The description also includes holder routing and connectors, fluid ports for supplying buffers to reaction vessels, and embodiments using air-inflated secondary chambers to deploy the container. A remote bladder and load-cell monitor measures container pressure. The supplied partial content does not include the background section, so the problem being solved is not explicitly described in patent.
Claims Coverage
The supplied claims include one independent claim, claim 1, and its coverage contains four main inventive features.
Disposable container with end connectors
A disposable container has first and second ends, one or more attachment connectors at the first end, and one or more conveyance connectors at the second end.
Holder with receiving connectors
A holder has upper, lower, and side surfaces, a front section and a rear section, and receiving connectors in the front section connected to the container's attachment connectors.
Mechanism for horizontal conveyance
The holder comprises at least one mechanism for horizontally conveying the disposable container from an undeployed to a deployed configuration.
Conveyance means connected to the container
One or more pulleys, cables, lines, strings, ropes, chains, treads, and/or telescoping rods connect to the disposable container through its conveyance connectors. Engagement changes the container from the undeployed configuration to the deployed configuration, extending it horizontally along the holder's interior surface.
The independent claim covers a disposable container, a holder with receiving connectors and a horizontal conveyance mechanism, and a connected conveyance means that extends the container from an undeployed to a deployed configuration.
Stated Advantages
Not explicitly described in patent.
Documented Applications
The description identifies fluid ports and connections for supplying buffers from a fluid source to reaction vessels.
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