Stent device with stent covering with regions of differing porosity
Inventors
Assignees
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Publication Number
US-12303410-B2
Publication Date
2025-05-20
Expiration Date
Abstract
A stent device including a stent cover having differing porosity ratio is disclosed. The stent covers the stent body comprising of stent wires and stent cells enclosed by the stent wires. The stent cover differs in porosity ratio for areas covering the stent wires and the areas covering the stent cells. The porosity ratio for areas covering the stent wires may have a higher porosity rate in order to promote endothelialization of the stent device. A bilayer stent cover differing in porosity ratio may be used to cover the stent body, as well as stent cover not covering the entirety of the stent body.
Core Innovation
The disclosed invention relates to a self-expanding stent in which a cover is configured to cover at least part of a braided stent body. The stent body has a plurality of cells surrounded by stent wires, and the cover includes portions or regions with different porosity ratios. The porosity pattern is spatially arranged so that higher porosity is provided in regions corresponding to the wires, while lower or nonporous porosity is provided in regions corresponding to the cells.
In the described configuration, a porosity ratio of a first portion of the cover is higher than a porosity ratio of a second portion, and a porosity ratio of a third portion is lower than the porosity ratio of the first portion while remaining higher than the porosity ratio of the second portion. The porosity pattern is arranged so that the first, second, and third portions correspond to first, second, and third areas of a cell. This spatial correspondence is used to promote endothelialization and anchoring at wire-aligned regions while suppressing ingrowth in low-porosity regions aligned with open-cell or void areas.
The disclosure further describes embodiments with longitudinal and circumferential porosity patterning and different geometric arrangements of low-porosity regions, including center versus edge porosity patterning and stepped or gradient regions. It also describes bilayer or dual-cover configurations in which an outer cover and an inner cover are provided, including possible gaps and adhered overlap portions with reduced effective porosity.
Claims Coverage
The partial document contains two independent claims. Across these, the core inventive concept is the spatial correspondence between braided stent wires/cells and cover regions or portions with differing porosity ratios, with specified relative ordering of the porosity ratios or explicit high- versus low-porosity region placement.
Porosity-ratio portion alignment across cell areas
A stent in which a body is braided by one or more wires and has plurality of cells surrounded by the wires, and one cell has first area, second area, and third area; the cover has first portion, second portion, and third portion corresponding to the first, second, and third areas; the second portion is surrounded by the first portion; a porosity ratio of the first portion is higher than a porosity ratio of the second portion; a porosity ratio of the third portion is lower than the porosity ratio of the first portion; and a porosity ratio of the third portion is higher than the porosity ratio of the second portion.
High- and low-porosity regions correspond to wires and cells
A stent having a body braided by one or more wires with a plurality of cells surrounded by the wires, and a cover configured to cover at least part of the body; the cover includes one or more high porosity regions and one or more low porosity regions in an area where the cells are covered; the one or more low porosity regions correspond in location to one or more of the cells; and the one or more high porosity regions correspond in location to the one or more wires.
Overall claim coverage is directed to covers with spatially differing porosity ratios that are aligned with the braided stent geometry, using either multi-portion comparative porosity ordering within a cell or co-located high-porosity and low-porosity regions.
Stated Advantages
Promotes endothelialization and anchoring at high-porosity regions aligned with stent wires.
Suppresses ingrowth at low-porosity regions aligned with open-cell or void areas.
Reduces clogging.
Documented Applications
A covered self-expanding stent context is described, including suppression of ingrowth, promotion of endothelialization and anchoring, and reduction of clogging compared to related porous or nonporous coverage approaches.
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