Counterpulsation device driver apparatus, method and system
Inventors
Spence, Paul • Dowling, Rob • Kung, Robert T. V. • Siess, Thorsten • Gratz, Eric • Spanier, Gerd
Assignees
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Publication Number
US-12280251-B2
Publication Date
2025-04-22
Expiration Date
Abstract
A method of operating a counterpulsation device (CPD) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a CPD drive line in pneumatic communication with the CPD to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a CPD drive line pressure signal indicative of the pressure in the CPD drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal.
Core Innovation
The invention relates to a counterpulsation device (CPD) including a blood chamber, a drive chamber, and a membrane configured to separate the blood chamber from the drive chamber. The CPD further includes a CPD drive line in pneumatic communication with the drive chamber and a controller configured to control a pressure supplied to the CPD drive line. The controller causes the CPD to alternately fill with blood and eject blood, with timing determined at least in part based on a heartbeat signal indicative of a heartbeat of a subject.
The controller receives a CPD drive line pressure signal indicative of the pressure in the CPD drive line and adjusts the pressure supplied to the CPD drive line based at least in part on the CPD drive line pressure signal. The controller performs exposing the CPD drive line to a negative pressure to fill the blood chamber as the heart of the subject is contracting and exposing the CPD drive line to a positive pressure to empty the blood chamber as the heart of the subject is relaxing.
The controller is further configured to adjust the pressure supplied to the CPD drive line by analyzing the CPD drive line pressure signal to determine a full condition or an empty condition of the CPD by analyzing change in drive line pressure as a function of time. The disclosure also describes CPD architecture using vacuum and pressure chambers and drive line valves to enable pneumatic exposure and sensing via a CPD drive line sensor.
Claims Coverage
The independent claim covers a CPD with heartbeat-based timing of alternating fill and eject and closed-loop adjustment using analysis of the CPD drive line pressure signal over time to determine full and empty conditions.
Heartbeat-determined alternating fill and eject timing using CPD drive line pressure control
A controller receives a heartbeat signal indicative of a heartbeat of a subject and controls a pressure supplied to the CPD drive line to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heartbeat signal.
Pneumatic negative-pressure fill during contraction and positive-pressure empty during relaxation
Adjusting the pressure supplied to the CPD drive line is performed by exposing the CPD drive line to a negative pressure to fill the blood chamber as the heart of the subject is contracting and exposing the CPD drive line to a positive pressure to empty the blood chamber as the heart of the subject is relaxing.
Closed-loop full/empty detection from drive-line pressure change over time
The controller adjusts the pressure supplied to the CPD drive line by analyzing the CPD drive line pressure signal to determine a full condition or an empty condition of the CPD by analyzing change in drive line pressure as a function of time.
Overall, the claim set is centered on heartbeat-synchronized CPD operation that is refined by closed-loop analysis of CPD drive line pressure over time to determine full and empty conditions, and then adjust pneumatic pressure supply accordingly.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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