Device for monitoring the pressure or alternatively an injection force of a plurality of jets generated at the outlet of a needleless injection device
Inventors
AURIEL, Christophe • JAUMARY, Ludovic • Robin, Maxime • SIMONNEAU, Brice
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Assignees
Member
CrossjectCrossject is a specialty pharmaceutical company focused on drug-device combination products for emergency medicine. Leveraging a proprietary needle-free auto-injection platform, the company develops and manufactures fast-acting treatments for life-threatening situations such as epilepsy, adrenal crisis, and anaphylaxis. Crossject conducts advanced regulatory development, clinical validation, and large-scale industrialization to deliver innovative therapies for global markets, with an emphasis on simplicity, reliability, and patient usability.
Crossject is a specialty pharmaceutical company focused on drug-device combination products for emergency medicine. Leveraging a proprietary needle-free auto-injection platform, the company develops and manufactures fast-acting treatments for life-threatening situations such as epilepsy, adrenal crisis, and anaphylaxis. Crossject conducts advanced regulatory development, clinical validation, and large-scale industrialization to deliver innovative therapies for global markets, with an emphasis on simplicity, reliability, and patient usability.
Publication Number
US-12280245-B2
Publication Date
2025-04-22
Expiration Date
Abstract
A monitoring device for monitoring a pressure or an injection force of a plurality of jets generated by channels at an outlet of a nozzle of a needleless injection device. The monitoring device includes a plurality of measuring elements. Each of the plurality of measuring elements are configured to measure the pressure or the injection force of a corresponding jet of the plurality of jets. Each of the plurality of measuring elements include a receiving face oriented to receive the corresponding jet.
Core Innovation
The invention relates to a monitoring device for monitoring a pressure of or an injection force of a plurality of jets generated by channels at an outlet of a nozzle of a needleless injection device. The monitoring device includes a plurality of measuring elements, each configured to measure the pressure of or the injection force of a corresponding jet, and each measuring element comprises a receiving face oriented to receive the corresponding jet.
At least one receiving face is inclined with respect to a plane orthogonal to a direction of propagation of the corresponding jet. The inclined receiving face is implemented as distinct and/or by tilting along the sensor length, and the measuring elements are described as pressure sensors or injection force sensors, optionally including pencil/piezoelectric configurations, with attached parts that provide a beveled receiving face and a mechanical transmission element.
A support is provided for the measuring elements, including indexing lugs/fingers for radial and/or axial alignment of the measuring elements. A partitioning member with separators can be included to prevent neighboring jets from affecting adjacent receiving faces, and an indexing element positions nozzle channels opposite the measuring elements, enabling independent jet-by-jet measurement. The document also mentions an assembly including a needleless injection device and a monitoring device.
Claims Coverage
The independent claim family feature set comprises one inventive theme: monitoring a plurality of jets of a needleless injection nozzle by using multiple measuring elements having jet-receiving faces, with at least one receiving face inclined relative to a plane orthogonal to the jet direction of propagation.
Inclined receiving face for jet-by-jet monitoring
A monitoring device includes a plurality of measuring elements, each configured to measure the pressure of or the injection force of a corresponding jet, wherein each measuring element comprises a receiving face oriented to receive the corresponding jet, and wherein the receiving face of at least one measuring element is inclined with respect to a plane orthogonal to a direction of propagation of the corresponding jet.
The claim coverage is centered on multiple measuring elements aligned to respective jets and at least one inclined receiving face relative to the jet propagation direction; dependent refinements further define how the inclination is achieved, specify measuring-element sensor constructions, add mechanical indexing and separation to limit neighboring-jet influence, and enable independent jet-by-jet measurement via indexing of nozzle channels.
Stated Advantages
Documented Applications
An assembly including a needleless injection device and a monitoring device is described, where the monitoring device monitors pressure of or injection force of jets at the outlet of a needleless injection device nozzle.
Example active ingredients are provided, including methotrexate, adrenaline, sumatriptan, hydrocortisone, naloxone, midazolam, apomorphine, and enoxaparin sodium.
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