Leadless cardiac pacemaker device configured to provide intra-cardiac pacing

Inventors

Swenson, Kurt • GUHANIYOGI, SHAYAN • Reddy, Ravi Kiran Kondama • Jones, Christopher • MIDGETT, MADELINE ANNE • Whittington, R. Hollis

Assignees

Biotronik SE and Co KG

Abstract

A leadless pacemaker device configured to provide for an intra-cardiac pacing, including: processing circuitry configured to generate ventricular pacing signals for stimulating ventricular tissue, and a reception device for receiving a sensing signal indicative of an atrial activity, wherein the processing circuitry is configured to detect an atrial event derived from said sensing signal, wherein the atrial event is a valid atrial sense event, where a series of atrial events lie within a range for a normal atrial rate, and/or when the atrial rate variability is within a certain range indicating a regular atrial rhythm, wherein in case a valid atrial sense event is detected, the processing circuitry is further configured to: determine ventricular pacing events according to atrial events, calculate ventricular-atrial time delays, determine a correction value based a measured time delay and the calculated time delay, and adjust the ventricular pacing timing based on the correction value.

Core Innovation

The invention relates to a leadless pacemaker device configured to provide for an intra-cardiac pacing and to generate ventricular pacing signals for stimulating ventricular tissue. The device includes processing circuitry and a reception device for receiving a sensing signal indicative of atrial activity. The processing circuitry detects an atrial event derived from the sensing signal and determines whether the atrial event is a valid atrial sense event, where a series of atrial events lie within a range for a normal atrial rate and/or when the atrial rate variability is within a certain range indicating a regular atrial rhythm.

When a valid atrial sense event is detected, the processing circuitry determines a ventricular pacing event according to the atrial event based on a calculated atrial-ventricular (AV) delay. The processing circuitry further determines a calculated ventricular-atrial delay (VA_calc) indicative of a time delay at which an atrial event (As) is predicted to occur following a prior ventricular event (Vs). The processing circuitry measures a true occurrence of a time delay (VA_true) at which an atrial event (As) occurs following a prior ventricular event (Vs).

The processing circuitry determines a correction value (CV) based on a timing relation between VA_true and the calculated ventricular-atrial delay (VA_calc). The processing circuitry then adjusts the ventricular pacing timing based on the correction value (CV), thereby using the measured true VA timing relative to the predicted VA timing to correct subsequent ventricular pacing timing.

Claims Coverage

The document provides two independent claims covering detection of valid atrial sense events and correction of intra-cardiac ventricular pacing timing based on the timing relationship between a calculated ventricular-atrial delay and a measured true ventricular-atrial delay. The inventive core includes atrial validity determination, prediction of VA_calc after a prior ventricular event, measurement of VA_true after that prior ventricular event, computation of a correction value CV from their timing relation, and adjustment of ventricular pacing timing based on CV.

The claim set focuses on atrial-tracked intra-cardiac ventricular pacing where ventricular timing is predicted using VA_calc derived from AV timing, then corrected by measuring the true VA occurrence (VA_true) and computing a correction value (CV) from the timing relation between VA_true and VA_calc to adjust ventricular pacing timing.

Stated Advantages

Documented Applications