Systems and methods for removing undesirable material within a circulatory system

Inventors

Aklog, Lishan • Glennon, Michael

Assignees

Angiodynamics Inc

Abstract

A system is provided which includes a cannula and a secondary device. The cannula includes an expandable member, a cannula lumen, and a cannula proximal end. The expandable member includes a proximal most end, a distal most end, at least two movable sections, with the space between the at least two moveable sections, and an impermeable membrane extending across the space between each of the at least two moveable sections. In addition, the impermeable membrane extends from the expandable member distal most end to the expandable member proximal most end. The secondary device is configured to be coaxially placed through the cannula lumen. The cannula proximal end is configured to operatively couple to a vacuum source configured to create a negative pressure to pull an undesirable material into the cannula lumen.

Core Innovation

The invention provides a closed system for treatment of undesirable material within a vasculature of a body by aspirating the undesirable material and blood through an aspiration cannula or suction cannula into a reservoir or container. The aspirated undesirable material is filtered to produce filtered blood, and the filtered blood is reinfused through a reinfusion cannula into the vasculature. This includes coupling a reservoir or container in fluid communication with a filter assembly and a pump, and driving the portion of the undesirable material and aspirated blood through the filter assembly into the pump before reinfusion.

A core aspect of the disclosed approach is the combination of suction and reinfusion using a cannula arrangement that supports endovascular retrieval while handling blood as a filtered, reinfused fluid. The disclosed method includes filtering the portion of clot or undesirable material from aspirated blood to produce filtered blood, and driving the filtered blood from the pump through the reinfusion cannula into the vasculature. The dependent claim refinements further specify reservoir or container configurations and cannula configurations such as a single multi-lumen catheter and coaxial placement of suction and reinfusion cannulae.

Another core aspect is using a secondary device with an expandable element to disrupt or dislodge at least a portion of the undesirable material prior to aspiration. The invention includes placing a secondary device coaxially through a lumen of a first or aspiration/suction cannula, expanding an expandable element coupled to a distal end of the secondary device, and disrupting at least a portion of the undesirable material by engaging at least a portion of the undesirable material with the expandable element. The disrupted material and blood are then aspirated through the cannula into a container for filtration and reinfusion.

Claims Coverage

The partial content includes three independent claims (clm-00001, clm-00010, and clm-00015) that share a common inventive framework: aspirate undesirable material and blood into a reservoir or container, filter the aspirate to produce filtered blood, and reinfuse the filtered blood via a reinfusion cannula. Across the independent claims, the inventive coverage is implemented with several main inventive features, including closed reservoir or container-to-filter-to-pump reinfusion flow, cannula-based aspiration at a treatment site, and optional secondary coaxial expandable disruption prior to aspiration.

Across clm-00001, clm-00010, and clm-00015, the claim coverage is directed to a filtration-and-reinfusion workflow in which aspirated undesirable material and blood are collected, filtered to produce filtered blood, and reinfused through a reinfusion cannula. In addition, the scope includes the use of a coaxially placed secondary device with an expandable element to disrupt undesirable material prior to aspirating the disrupted material for filtration and reinfusion.

Stated Advantages

Documented Applications