Multidrug pain management package

Inventors

Steinberg, David L. • Loskove, Joseph • Thompson, Hannah

Abstract

Disclosed herein is a multidrug pain management package to dispense two or more medicaments to treat pain comprising a primary n-polygon, and one or more concentric m-polygons, wherein each side of the n-polygon and m-polygons have at least n or m-medicament chambers capable of holding the two or more medicaments. Also disclosed herein is a multidrug pain management package comprising a disk, wherein the disk is divided into equally spaced regions, and wherein each region has chambers capable of holding medicaments. Also disclosed herein are single formulations to treat pain.

Core Innovation

The document describes a single formulation comprising acetaminophen, one or more nonsteroidal anti-inflammatory drug, and a gabapentinoid. The formulation further includes one or more additional active ingredients selected from anti-convulsants or anti-seizure medications, alpha 2 agonists, corticosteroids, H2 blockers, proton pump inhibitors, antacids, SSRIs, SNRIs, TCAs, muscle relaxants, sleep aids drugs, natural sleep aids, and magnesium.

The background described in the provided material frames the invention in terms of multidrug pain management and a pain-relief regimen using combined non-opioid components. The formulation is disclosed as a combined approach intended to manage pain by combining acetaminophen, an NSAID class, and a gabapentinoid with additional adjunct active ingredient classes.

The document also discloses multidrug pain management package/dispenser concepts using a blister-layer architecture with chambered medicament regions and rupturable/blister-canopy chambers, including optional inhaler dispensing with timed dose-locking. A prophetic clinical example is presented using self-reported NRS-11 pain scoring and structured dosing regimens for adults and children, including inhalation dosing interval examples.

Claims Coverage

The provided claim set includes one independent claim directed to a single formulation containing acetaminophen, an NSAID, a gabapentinoid, and specified classes of additional active ingredients. The independent claim is followed by dependent claims refining ingredient selection and/or dosage form/route and characterizing excipients and particular ingredient choices.

Overall, the claim coverage centers on a single combined pain-relief formulation that includes acetaminophen plus an NSAID plus a gabapentinoid, together with one or more additional active ingredients chosen from a specified list of adjunct classes.

Stated Advantages

Documented Applications

No documented applications found