Glufosinate additive for improved weed control
Inventors
Norsworthy, Jason Keith • Priess, Grant Lawson
Assignees
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Publication Number
US-12219958-B2
Publication Date
2025-02-11
Expiration Date
Abstract
Disclosed herein is a herbicide and methods for the control of a grass or a broadleaf weed in a crop. The herbicide comprises an effective amount glufosinate, or a salt thereof, and an effective amount of a metabolic inhibitor.
Core Innovation
The specification describes an herbicide composition for the control of a grass or a broadleaf weed in a crop. The herbicide comprises an effective amount of glufosinate, or a salt thereof, together with an effective amount of a metabolic inhibitor. The metabolic inhibitor is described as a glutathione S-transferase (GST) inhibitor, and the document states that the GST inhibitor is baicalin.
The document further describes that combining glufosinate with a metabolic inhibitor improves weed-control performance, particularly under low-light or low-humidity conditions. It also describes improved control for larger weeds and for weeds that are low-sensitivity or resistant. The specification additionally describes metabolic inhibitor classes and related compounds, including other GST inhibitors and inhibitors directed to glyoxylate pathway and cytochrome P450 activities, as well as certain polyphenols/ROS inducers.
The specification also discloses formulation options in which the herbicide composition includes adjuvants, including nonionic surfactants and oils. Field examples described in the document report reduced efficacy of glufosinate alone at night, and very high weed control with glufosinate combined with a GST inhibitor at night. The document also states that the compositions do not produce negative crop injury in the glufosinate-tolerant crops described in the specification.
Claims Coverage
The partial claim set includes one independent claim. The independent claim coverage centers on the herbicide formulation combining glufosinate (or a salt) with a specific metabolic inhibitor, where the inhibitor is baicalin as a glutathione S-transferase (GST) inhibitor.
Glufosinate plus baicalin as a GST metabolic inhibitor
An herbicide for the control of a grass or a broadleaf weed in a crop, comprising an effective amount of glufosinate, or a salt thereof, and an effective amount of a metabolic inhibitor comprising a glutathione S-transferase inhibitor, wherein the glutathione S-transferase inhibitor is baicalin.
Across the independent claim, the core inventive coverage is the use of an effective amount of glufosinate (or a salt) combined with an effective amount of a metabolic inhibitor in which the glutathione S-transferase inhibitor is baicalin.
Stated Advantages
Improves weed control, particularly under low-light or low-humidity conditions.
Provides improved control for larger weeds.
Provides improved control for low-sensitivity or resistant weeds.
Reported very high weed control when glufosinate is combined with a GST inhibitor at night.
Does not produce negative crop injury in the glufosinate-tolerant crops described in the document.
Documented Applications
Herbicide use for the control of a grass or a broadleaf weed in a crop using a formulation comprising glufosinate (or a salt) and a metabolic inhibitor comprising a glutathione S-transferase inhibitor (baicalin).
Weed-control use cases described as improved performance under low-light/night or low-humidity conditions.
Use described for control of larger weeds and for weeds described as low-sensitivity or resistant.
Crop contexts described include glufosinate-tolerant crops such as Enlist cotton, XtendFlex cotton, LibertyLink GT27 soybean, and LibertyLink corn.
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