Fluid test cartridge, fluid test apparatus including the same, and method for controlling the fluid test apparatus
Inventors
TAK, Yu Kyung • Park, Sung Ha • Taguchi, Takayuki
Assignees
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Publication Number
US-12174180-B2
Publication Date
2024-12-24
Expiration Date
Abstract
A fluid test cartridge, a fluid test apparatus, and a method for controlling the same. The fluid test apparatus includes a housing, and a fluid test cartridge that is accommodated in the housing. The fluid test cartridge includes at least one chamber in which a fluid sample to be tested and a drying reagent can be accommodated. The fluid test apparatus includes a light emitter configured to emit light to the at least one chamber, a light sensor, and a processor configured to detect a concentration of a first material in the fluid sample. The drying reagent includes a non-metallic particle bound to a second material that specifically binds to the first material. Tests can thus be carried out over a wider range of wavelengths, and testing errors can be reduced.
Core Innovation
A fluid test apparatus is provided that includes a housing and a fluid test cartridge accommodated in the housing. The fluid test cartridge includes an array of chambers configured to accommodate a fluid sample and a drying reagent, and the apparatus includes a light emitter and a light sensor to detect an optical property of a first material included in the fluid sample based on the received light.
The drying reagent includes a non-metallic particle bound to a second material that specifically binds to the first material. The non-metallic particle is a nano-sized particle selected from a carbon nanoparticle, a ceramic nanoparticle, and a polymeric nanoparticle, and the non-metallic particle absorbs an entire wavelength of visible light.
The array of chambers includes a first chamber accommodating a first drying reagent and a second chamber accommodating a second drying reagent. The first drying reagent comprises a first amount of an internal standard material included in the fluid sample, the second drying reagent comprises a second amount of the internal standard material included in the fluid sample, and preset concentrations are mapped to identification information associated with the fluid test cartridge. The second material of the first drying reagent is different from the second material of the second drying reagent so that the first drying reagent measures a first concentration of the first material and the second drying reagent measures a second concentration of the first material different from the first concentration.
Claims Coverage
The document provides three independent claims directed to a fluid test apparatus, a fluid test cartridge, and a method for controlling a fluid test apparatus. The inventive coverage centers on optical detection of a first material and determination of concentration using a drying reagent that includes a non-metallic nano-sized particle absorbing visible light.
Visible light absorbing non-metallic nano-sized binding drying reagent
The drying reagent includes a non-metallic particle bound to a second material that specifically binds to the first material, wherein the non-metallic particle is a nano-sized particle selected from carbon nanoparticle, ceramic nanoparticle, and polymeric nanoparticle, and wherein the non-metallic particle absorbs an entire wavelength of visible light.
Optical emitter-sensor concentration determination using chamber array
A light emitter emits light towards an array of chambers, and a light sensor receives the light incident on the array of chambers to detect an optical property of a first material included in the fluid sample; a processor determines a concentration of the first material based on the optical property detected by the light sensor.
Chamber-specific drying reagents with mapped internal standard concentrations
The array of chambers includes a first chamber accommodating a first drying reagent and a second chamber accommodating a second drying reagent, wherein the first drying reagent comprises a first amount of an internal standard material and the second drying reagent comprises a second amount of the internal standard material, and preset concentrations are mapped to identification information associated with the fluid test cartridge.
Different binding materials across chambers to measure different concentrations
The second material of the first drying reagent is different from the second material of the second drying reagent such that the first drying reagent measures a first concentration of the first material and the second drying reagent measures a second concentration of the first material different from the first concentration.
Antigens and antibodies specific binding in drying reagent
The first material is antigens and the second material is antibodies.
Fluid test cartridge configuration with inlet and tester chamber array
A fluid test cartridge includes an inlet through which a fluid sample is introduced, and a tester configured to receive the fluid sample from the inlet and to test the fluid sample, wherein the tester comprises an array of chambers that accommodates the fluid sample introduced through the inlet and a drying reagent including a nonmetallic particle bound to a second material that specifically binds to a first material included in the fluid sample.
Controlling by reacting and analyzing an optical property
A method for controlling a fluid test apparatus comprises providing a fluid test apparatus and then reacting the fluid sample with the first drying reagent and/or the second drying reagent, and analyzing a reaction in the fluid test cartridge by measuring an optical property of the first material with the light sensor.
Separate optical property measurements for first and second chambers
Analyzing includes measuring an optical property of the first material in a first chamber and an optical property of the first material in a second chamber using the light sensor.
Across the independent claims, the core inventive coverage is directed to optical detection and concentration determination for a first material using an array of chambers, where a drying reagent includes a visible-light-absorbing non-metallic nano-sized particle bound to a binding material. The claims additionally cover using chamber-specific drying reagents with internal standard amounts mapped to cartridge identification and using different binding materials for different chamber-based measurements of antigen concentration.
Stated Advantages
Documented Applications
No documented applications found
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