Coating a working wire for a continuous biological sensor
Inventors
Boock, Robert James • Zhang, Huashi • Gu, Wei
Assignees
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Abstract
Methods for coating a working wire for a continuous biological sensor include providing a plurality of wires in a fixture and dipping the plurality of wires into a coating solution according to parameters for a dipping process. A plurality of diameters is measured along a length of at least two coated wires of the plurality of wires in the fixture, using an automated measurement system, as in an in-line process. A controller that is in communication with the automated measurement system determines a thickness difference, the thickness difference being a difference between a thickness setpoint and an aggregate criteria for the plurality of diameters. The controller calculates adjusted parameters for the dipping process based on the thickness difference.
Core Innovation
The invention provides a method for coating a working wire for a continuous biological sensor. A plurality of wires are provided in a fixture, and the wires are dipped into a coating solution according to parameters for a dipping process, supporting coating more than one wire during manufacturing by performing the coating using a dipping process applied to the plurality of wires in the fixture.
During the dipping process, an automated measurement system performs in-line measuring of a plurality of diameters along a length of at least two coated wires in the fixture. A controller determines a thickness difference between a thickness setpoint and an aggregate criteria for the plurality of diameters, and then calculates adjusted parameters for the dipping process based on the thickness difference.
The controller can calculate adjusted parameters that include changes to dipping parameters based on the measured thickness difference. The method refines the determining and calculating by using aggregate criteria such as variance, including variance determined across wires in the fixture. The method can also incorporate viscosity of the coating solution by determining the viscosity and choosing a correlation from a set of correlations based on the viscosity, and can incorporate environmental factors such as airflow and relative humidity of the airflow.
Claims Coverage
The independent claim covers a closed-loop, inline measurement and control approach for coating a plurality of wires by dipping, where diameter measurements along multiple coated wires are used to compute a thickness difference versus a thickness setpoint and then adjust dipping process parameters. Dependent claims further narrow the aggregate criteria used for the thickness difference, including variance forms, and specify example adjusted-parameter changes and factor selections, including withdrawal speed and viscosity-based correlation selection.
In-line diameter measurement along multiple coated wires in a fixture
Measuring, as an in-line process, a plurality of diameters along a length of at least two coated wires of the plurality of wires in the fixture, using an automated measurement system.
Controller-determined thickness difference from thickness setpoint and aggregate criteria
Determining, by a controller that is in communication with the automated measurement system, a thickness difference, the thickness difference being a difference between a thickness setpoint and an aggregate criteria for the plurality of diameters.
Adjusted dipping parameters calculated from thickness difference
Calculating, by the controller, adjusted parameters for the dipping process based on the thickness difference.
Thickness difference determined using variance of diameters
The thickness difference comprises using a variance of the plurality of diameters.
Variance defined as cross-fixture diameter difference between wires on different sides
The variance comprises a difference in diameters between a first coated wire and a second coated wire mounted on different sides of the fixture.
Adjusted parameters change withdrawal speed with a control objective for minimizing dips
Calculating the adjusted parameters comprises changing a withdrawal speed to minimize a number of dips for achieving the thickness setpoint within a target window.
Environmental factors include airflow and relative humidity of the airflow
The environmental factors comprise an airflow and a relative humidity of the airflow.
Viscosity-based correlation selection for thickness versus withdrawal speed
Determining a viscosity of the coating solution; and choosing a correlation in the set of correlations based on the viscosity.
Overall, claim coverage centers on using inline diameter measurements across multiple coated wires to compute a thickness difference relative to a thickness setpoint using aggregate criteria, and then calculating adjusted dipping process parameters based on that difference. The dependent refinements specify variance-based thickness-difference calculations, example cross-fixture variance definitions, example adjustment via withdrawal speed under a target window objective, and further refinements incorporating environmental factors and viscosity-based correlation selection.
Stated Advantages
Improves accuracy of coating by using in-line diameter measurement and controller-based adjustment based on the thickness difference versus a thickness setpoint.
Supports efficient processing by enabling multiple wires in a fixture to be coated while measuring diameters inline during the dipping process.
Can reduce or avoid overshoot by adjusting dipping parameters based on the measured thickness difference.
Can improve throughput compared with conventional post-process measurement and fixed dip settings.
Documented Applications
Manufacturing a working wire for a continuous biological sensor, including a continuous glucose monitor, using an automated dipping and in-line optical measurement/control approach.
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