Device for the continuous monitoring of blood characteristic quantities in an external cardiovascular supporting circuit
Inventors
Petralia, Antonio • Ghelli, Nicola • BELLIATO, Mirko
Assignees
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Publication Number
US-12059518-B2
Publication Date
2024-08-13
Expiration Date
Abstract
A device for the continuous monitoring of blood characteristic quantities in an external cardiovascular supporting circuit, said circuit including a venous line which conveys blood from the patient to an oxygenator, and along which at least one pump is arranged, and an arterial line which returns blood from the oxygenator to the patient, where said oxygenator comprises at least one blood inlet port connected to said venous line and at least one blood outlet port connected to said arterial line, at least one inlet channel and at least one outlet channel of a work gas intended to supply oxygen to the blood and/or to remove carbon dioxide from the same.
Core Innovation
The invention provides a device for the continuous monitoring of blood characteristic quantities in an external cardiovascular supporting circuit in which blood is conveyed from a patient to an oxygenator through a venous line and returned from the oxygenator to the patient through an arterial line. The oxygenator comprises work-gas inlet channels intended to supply oxygen to the blood and/or work-gas outlet channels intended to remove carbon dioxide from the same. The device continuously measures venous saturation (SAT V) of oxygen and arterial saturation (SAT A) of oxygen, and further measures blood flow (Qb) sent by a pump to the oxygenator and hemoglobin (Hb).
The device includes data entering means by the operator and an electronic control unit provided with a microprocessor operationally connected to a display. The microprocessor is adapted to receive the data measured by sensors for SAT V, SAT A, Qb, Hb, the measured quantity constituted by the flow of work gas (Gf), and the measured carbon dioxide concentration in the blood provided by at least one capnometer. The microprocessor is programmed to display in numerical form on the display the values of all the quantities measured and calculated, and in graphic form at least some of the values.
The microprocessor includes means adapted to calculate the quantity relating to the amount of carbon dioxide removed by the oxygenator (V′CO2ML) and the quantity relating to the amount of oxygen transferred by the oxygenator (V′O2ML). In addition, the device comprises acquisition means for acquiring the quantity relating to the amount of carbon dioxide removed from the patient’s lung (V′CO2NL) and means adapted to calculate the quantity relating to total removed carbon dioxide (V′CO2total).
Claims Coverage
Independent claim clm-00001 defines the core device for continuous monitoring in an external cardiovascular supporting circuit and includes eight inventive features around sensing, microprocessor-based calculation of oxygen transfer and carbon dioxide removal by the oxygenator, acquisition of patient-lung carbon dioxide removal, and numerical/graphical display. No other independent claims are provided in the provided claim list.
Continuous monitoring using venous and arterial oxygen saturation sensors
A first sensor connected to the venous line and a second sensor connected to the arterial line for continuous measurement of venous saturation (SAT V) of oxygen and arterial saturation (SAT A) of oxygen.
Blood flow sensing in the venous line
At least a third sensor inserted along the venous line for continuous measurement of the flow of blood (Qb) sent by the pump to the oxygenator.
Hemoglobin measurement in the circuit
At least a fourth sensor inserted in a point of the external cardiovascular supporting circuit for continuous measurement of hemoglobin (Hb).
Operator data entry with microprocessor control and display
Data entering means by the operator; and an electronic control unit with a microprocessor connected to a display, the microprocessor receiving data measured by the first, second, third and fourth sensors and the data entered by the operator, and making them appear at least partially on the display.
Work-gas flow sensing and capnometer carbon dioxide concentration measurement
At least a fifth sensor inserted in a point of the external cardiovascular supporting circuit for continuous measurement of the flow of work gas (Gf); and at least one capnometer inserted in a point of the external cardiovascular supporting circuit adapted to measure concentration of carbon dioxide in the blood.
Oxygen transfer and oxygenator carbon dioxide removal calculations
Microprocessor means adapted to calculate the quantity relating to the amount of carbon dioxide removed by the oxygenator (V′CO2ML) and the quantity relating to the amount of oxygen transferred by the oxygenator (V′O2ML).
Numerical and graphic display of measured and calculated values
Microprocessor programmed to display in numerical form on the display the values of all the quantities measured and calculated and in graphic form at least some of said values.
Acquisition of patient-lung carbon dioxide removal and total carbon dioxide calculation
Acquisition means for acquiring the quantity relating to the amount of carbon dioxide removed from the patient’s lung (V′CO2NL) and means adapted to calculate the quantity relating to total removed carbon dioxide (V′CO2total).
The provided independent claim defines a continuously monitored external cardiovascular supporting circuit by combining venous/arterial oxygen saturation sensing, blood flow and hemoglobin sensing, work-gas flow and capnometer carbon dioxide concentration measurement, operator input with a microprocessor-driven control/display, and calculation of V′CO2ML and V′O2ML together with acquisition of V′CO2NL and calculation of V′CO2total.
Stated Advantages
Not explicitly described in patent.
Documented Applications
External cardiovascular supporting circuit monitoring in ECMO/ECLS/CPB contexts as described in the partial content.
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