Vascular and aortic grafts and deployment tool

Inventors

Palermo, Thomas J. • Lee, Pin-Hsuan • Jen, Jimmy

Assignees

Aquedeon Medical Inc

Abstract

A hybrid graft and method for implantation in a blood vessel of a patient is described. The hybrid graft may include a graft portion having proximal and distal ends and an expandable mesh secured to the distal end of the graft portion. The expandable mesh is configured to transition from an insertion to a deployed diameter. The hybrid graft may also include a tubular sleeve having a lumen configured to receive a part of the graft portion and the expandable mesh and a suture cuff positioned adjacent the expandable mesh. During deployment, the distal end of the hybrid graft is inserted through an opening in the blood vessel wall or an end of the vascular graft and expanded from the insertion to the deployed diameter to secure the hybrid graft within the blood vessel or vascular graft. The suture cuff is sutured to the blood vessel or vascular graft.

Core Innovation

The disclosure describes a hybrid graft for implantation in a blood vessel of a patient, including a graft portion having proximal and distal ends. An expandable mesh is secured to the distal end of the graft portion and is configured to transition from an insertion diameter to a deployed diameter. A tubular sleeve having a lumen receives at least a part of the graft portion and the expandable mesh, and a suture cuff formed by a portion of the tubular sleeve is positioned adjacent the expandable mesh.

The disclosure further refines the suture cuff configuration in relation to the expandable mesh when unrolled, including the suture cuff reaching the distal end of the expandable mesh when the mesh is unrolled. An initial suture cuff configuration includes a ring rolled around a longitudinal centerline proximally from the expandable mesh, and an example specifies expanded polyethylene terephthalate (ePET) for the graft portion.

The disclosure also describes the expandable mesh as self-expandable and secured to the distal end of the graft portion by sintering. Additional system and deployment concepts include vascular graft anchors and aortic central hybrid graft constructs with jumper grafts, including optional expandable mesh tips and suture bands, along with related guidance and perfusion elements referenced in the disclosure.

Claims Coverage

Independent claim clm-00001 defines the core hybrid-graft structure and includes four main inventive components: an expandable mesh on a graft portion, an insertion-to-deployed diameter transition, a tubular sleeve lumen receiving the graft portion and mesh, and a suture cuff formed by the sleeve portion adjacent the expandable mesh. Dependent claims further narrow the suture-cuff configuration, mesh behavior, graft material, and the mechanism of securing the mesh to the graft portion.

Across the independent claim and its dependents, coverage centers on a hybrid graft architecture with an expandable mesh on a distal graft end that transitions from an insertion diameter to a deployed diameter, received within a tubular sleeve lumen, together with a sleeve-formed suture cuff positioned adjacent the mesh. Dependent refinements specify relative suture-cuff extension when unrolled, an initially rolled cuff-ring configuration, graft material as ePET, self-expandable mesh behavior, and mesh attachment to the distal end by sintering.

Stated Advantages

Documented Applications

No documented applications found