Head modeling for a therapeutic or diagnostic procedure
Inventors
Mainkar, Neeraj • Pillutla, Ravi • Ghiron, Kenneth Marc • Riehl, Mark Edward
Assignees
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Publication Number
US-12020804-B2
Publication Date
2024-06-25
Expiration Date
Abstract
A model of a human subject's head may be generated to assist in a therapeutic and/or diagnostic procedure. A treatment and/or diagnostic system may generate a fitted head model using a predetermined head model and a plurality of points. The plurality of points may include facial feature information and may be determined using a sensor, for example, an IR or optical sensor. One or more anatomical landmarks may be determined and registered in association with the fitted head model using the facial feature information, for example, without the use of additional image information, such as an MM image. The fitted head model may include visual aids, for example, anatomical landmarks, reference points, marking of the human subject's MT location, and/or marking of the human subject's treatment location. The visual aids may assist a technician to perform the therapeutic and/or diagnostic procedure of the human subject.
Core Innovation
A system and method for performing a transcranial magnetic stimulation (TMS) procedure determine a location of one or more anatomical landmarks of a human subject's head using a sensor. The anatomical landmarks comprise one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points. Using these anatomical landmarks, a processor determines a motor threshold location or a treatment location for the human subject on a head model.
The motor threshold location or the treatment location is determined on the head model without requiring the use of MRI information, x-ray image information, or CT image information of the human subject. In this way, the system determines the locations for TMS based on sensor-derived landmark information rather than additional imaging modalities. The determined motor threshold location or the treatment location is then used to perform the TMS procedure.
In various implementations, the system determines a location of anatomical landmarks and can determine a motor threshold location or treatment location using sensor feedback, captured images, and an indicator tool. The system can also generate a head model from sensor feedback without using MRI information, x-ray image information, or CT image information. Additionally, the system can include reference grids on the head model and can perform coil-position monitoring using a sensor to help control or stop the TMS procedure when a treatment coil position is outside a predefined range.
Claims Coverage
The document contains three independent claims (system, method, and system). Across these independent claims, the inventive coverage centers on sensor-based anatomical landmark localization and using those landmarks on a head model to determine a motor threshold location or treatment location for TMS without requiring MRI, x-ray, or CT image information, with optional refinements for sensor-image/indicator-point determination, head model generation from sensor feedback, and coil-position monitoring against a predefined range.
Sensor-based anatomical landmark determination for TMS
A system for performing a transcranial magnetic stimulation (TMS) procedure comprising a sensor; and a processor configured to determine a location of one or more anatomical landmarks of a human subject's head using the sensor, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject.
Motor threshold or treatment location on a head model without MRI/x-ray/CT
A system for performing a transcranial magnetic stimulation (TMS) procedure in which the processor determines a motor threshold location or a treatment location for the human subject on a head model using the anatomical landmarks without requiring the use of MRI information, x-ray image information, or CT image information of the human subject; and performs a TMS procedure based on the motor threshold location or the treatment location.
Sensor-based anatomical landmark determination and TMS placement without MRI/x-ray/CT
A method for performing a transcranial magnetic stimulation (TMS) procedure comprising determining a location of one or more anatomical landmarks of a human subject's head using a sensor, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject; determining a motor threshold location or a treatment location for the human subject on a head model using the anatomical landmarks without requiring the use of MRI information, x-ray image information, or CT image information of the human subject; and performing a TMS procedure based on the motor threshold location or the treatment location.
TMS system using sensor-defined landmarks to drive motor threshold or treatment locations
A system comprising a sensor; and a processor configured to determine a location of one or more anatomical landmarks of a human subject's head using the sensor, the anatomical landmarks comprising one or more of a nasion, an inion, a lateral canthus, an external auditory meatus, or one or more preauricular points of the human subject; and determine a motor threshold location or a treatment location for the human subject on a head model using the anatomical landmarks, wherein the motor threshold location or the treatment location is used for a transcranial magnetic stimulation (TMS) procedure.
Predefined-range treatment coil position monitoring with altering or stopping
A system in which the processor is configured to monitor a treatment coil's position during TMS, determine whether it falls outside a predefined positional range relative to the human head, and alter or stop the TMS procedure accordingly.
Sensor feedback-based head model generation
A system in which the processor generates a head model from sensor feedback without using MRI, x-ray, or CT image information, and then determines a motor threshold location or treatment location on the head model using anatomical landmarks and the sensor feedback.
Overall, the independent claims establish sensor-based determination of nasion/inion/lateral canthus/external auditory meatus/preauricular landmarks, and determination of a motor threshold location or treatment location on a head model for TMS without requiring MRI, x-ray, or CT image information. Dependent claim refinements further cover sensor-image/indicator-point determination, generating the head model from sensor feedback, and coil-position monitoring against a predefined positional range with altering or stopping.
Stated Advantages
Determine motor threshold location or treatment location on a head model without requiring MRI information, x-ray image information, or CT image information of the human subject.
Monitor a treatment coil position relative to a predefined positional range and alter or stop the TMS procedure accordingly.
Documented Applications
Performing a transcranial magnetic stimulation (TMS) procedure by determining motor threshold or treatment location using sensor-derived anatomical landmarks without requiring MRI, x-ray, or CT image information.
Neuronavigation and reuse of fitted head models for therapeutic/diagnostic procedures, including saving models for reuse across visits.
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