Modular vascular graft for low profile percutaneous delivery
Inventors
Chobotov, Michael V. • Whirley, Robert G. • Humphrey, Joseph W.
Assignees
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Publication Number
US-12016766-B2
Publication Date
2024-06-25
Expiration Date
Abstract
A hybrid modular endovascular graft wherein a main graft is sized to span at least a portion of a target vessel lesion in a large percentage of patients. Graft extensions may be secured to the main graft to extend the main graft and provide a sealing function for some applications.
Core Innovation
The invention relates to a hybrid modular endovascular graft system configured for low-profile percutaneous delivery. A bifurcated supple main graft spans thoracic/abdominal aortic lesions and includes a network of inflatable channels that can be filled with radiopaque and/or curable inflation material to provide rigidity and sealing.
The system further includes a proximal anchor member with a self-expanding proximal stent portion, a self-expanding distal stent portion, and struts disposed between adjacent crowns of the proximal stent portion and the distal stent portion. The struts and the self-expanding stent portions anchor the main graft in a body, including concepts for junctions/connectors such as a connector ring and connector elements with wire coils.
Ipsilateral and contralateral self-expanding graft extensions are deployed into open legs and are sealed and in fluid communication with corresponding lumens. Each extension includes a fluid flow lumen and PTFE/ePTFE multilayer coverings with an interposed helically wound stent, and retention/sealing can be enhanced using axial overlap and friction.
Claims Coverage
The provided independent claims are clm-00001, clm-00015, and clm-00018. Across these independent claims, the coverage centers on a modular graft assembly with a lumen graft, first and second stent graft extensions disposed in respective open ends, and a proximal anchor member with proximal and distal stent portions connected by integrally formed struts, together with a limitation on how the graft extensions expand in a deployed configuration.
Lumen graft with first and second stent graft extensions disposed in open ends
A graft having a lumen, a first open end and a second open end, and a first stent graft extension and a second stent graft extension, each comprising a stent and a layer of graft material, each extension being disposed in the first and second open end of the graft lumen.
Proximal anchor member with integrally connected proximal and distal stent portions and struts
A proximal anchor member for anchoring the graft in a body, including a proximal stent portion, a distal stent portion, and one or more struts disposed between adjacent crowns of the proximal stent portion and the distal stent portion, where each strut extends integrally between the proximal stent portion and the distal stent portion as part of a single piece of material.
Strut cross-sectional area relationship at the strut connection location
Each strut includes a cross sectional area that is the same as or greater than the cross sectional area of the proximal stent portion adjacent the strut at a location of connection to the proximal stent portion, or the distal stent portion adjacent the strut at a location of connection to the distal stent portion.
Graft extensions expand against a lumen portion without self-expanding or outward-radial-force actuated radial expansion
The first and second graft extensions in a deployed configuration expand against a portion of the graft lumen which does not comprise a self-expanding stent or a radially expandable stent that expands in a manner actuated by an outward radial force.
Across the independent claims, the invention is directed to a modular graft assembly with two stent graft extensions disposed in a lumen graft’s open ends and anchored by a proximal anchor member having proximal and distal stent portions connected by integrally formed struts. The claims further require that the graft extensions expand in a deployed configuration against a lumen portion that does not comprise a self-expanding stent or an outward-radial-force actuated radially expandable stent.
Stated Advantages
Provides rigidity and sealing when inflation material is used in a network of inflatable channels.
Documented Applications
For thoracic/abdominal aortic lesions, including abdominal aortic aneurysm (AAA) and thoracic aortic aneurysm (TAA).
For low-profile percutaneous delivery of an endovascular graft system.
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