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Publication Number

US-11992684-B2

Patent

Publication Date

2024-05-28

Expiration Date


Abstract

The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includes a stimulation related basic data storage module for storing stimulation related basic data,a stimulation related response data storage module for storing the stimulation related response data,a transfer module configured such that the stimulation related basic data are linked with and/or translated into the response data and/or artificial response data created by the transfer module, wherein the data generated by the transfer module are transfer data, the transfer data comprising link data and/or translation data and/or artificial response data,mapping module configured and arranged such that based on the stimulation related basic data and stimulation related response data and the transfer data a digital characteristic map is generated, andan analysis module configured and arranged such that the digital characteristic map is analyzed automatically.

Core Innovation

The invention relates to a system for planning and/or providing neuromodulation, especially neurostimulation. The system stores stimulation related basic data in a stimulation related basic data storage module and receives the stimulation related basic data via a first data input module, wherein the stimulation related basic data comprise stimulation descriptions. The system also stores stimulation related response data in a stimulation related response data storage module and receives the stimulation related response data via a second data input module, wherein the stimulation related response data comprise results triggered and received as response to the neuromodulation.

A transfer module is configured and arranged so that the stimulation related basic data received by the first data input module are linked with and/or translated into the stimulation related response data and/or artificial response data created by the transfer module. Data generated by the transfer module are transfer data, and the transfer data comprise data filling gaps where there is no direct link between the stimulation related basic data and the stimulation related response data. A transfer response data storage module stores the transfer data produced by the transfer module.

Based on the stimulation related basic data, the stimulation related response data, and the transfer data, a mapping module generates a digital characteristic map that describes an interrelation between the stimulation related basic data, the stimulation related response data, and the transfer data. An analysis module is configured and arranged such that the digital characteristic map is analyzed automatically, including identification of one or more of onset points, specificity points, and saturation points within the digital characteristic map.

Claims Coverage

The patent includes two independent claims: a system claim and a method claim. The inventive features cover storage and input of stimulation related basic data and stimulation related response data, transfer linking/translation into transfer data including artificial response data to fill gaps, digital characteristic map generation, automatic analysis, and identification of onset points, specificity points, and saturation points.

Storage and input of stimulation related basic data and stimulation descriptions

A stimulation related basic data storage module storing stimulation related basic data comprising stimulation descriptions, received via a first data input module.

Storage and input of stimulation related response data as triggered results

A stimulation related response data storage module storing stimulation related response data comprising results triggered and received as response to the neuromodulation, obtained via a second data input module.

Transfer linking/translation into transfer data including artificial response data to fill gaps

A transfer module configured to link and/or translate stimulation related basic data into stimulation related response data and/or artificial response data, wherein data generated by the transfer module are transfer data comprising data filling gaps where there is no direct link between stimulation related basic data and stimulation related response data.

Digital characteristic map describing interrelation among basic data, response data, and transfer data

A mapping module configured to generate, based on stimulation related basic data, stimulation related response data, and transfer data, a digital characteristic map describing an interrelation between the stimulation related basic data, the stimulation related response data, and the transfer data.

Automatic analysis of the digital characteristic map

An analysis module configured to analyze the digital characteristic map automatically.

Identification of onset points, specificity points, and saturation points

Automatically analyzing the digital characteristic map to identify one or more of onset points, specificity points, and saturation points within the digital characteristic map.

Across the independent claims, the core inventive approach is to link and/or translate stimulation descriptions into response data via transfer data, generate a digital characteristic map describing the interrelation among basic data, response data, and transfer data, and automatically analyze the map, including identification of onset, specificity, and saturation points.

Stated Advantages

Documented Applications

Planning and/or providing neuromodulation, especially neurostimulation, using a neuromodulation planning/provision system and corresponding method.

Example embodiments are described for spinal cord injury using epidural electrical stimulation (EES), with illustration of the digital characteristic map using stimulation-strength versus muscle-response curves.

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