Apparatus, methods, and systems for administering a medication to an animal
Inventors
Albert, Pradeep • Nichols, Christine • Condron, David J. • Artze, Brian • SABA, Fadi • Klein, Jesse • Vad, Vijay
Assignees
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Publication Number
US-11944742-B1
Publication Date
2024-04-02
Expiration Date
Abstract
A method for veterinary administration of medication to an animal, particularly a horse, is disclosed. The method involves inserting a capsule containing the medication, which is a liquid formulation, into a device connected to a tubular chamber. An atomizer is activated to atomize the medication, producing atomized medication. Before administration, a force is applied to a mask placed over the animal's muzzle, connected to the chamber. The atomized medication is then delivered to the animal. The liquid formulation, in some instances, comprises cells, cellular byproducts, or cell-derived products such as stem cells or products from human mesenchymal stem cells. This formulation may lack preservatives and may encompass peptides, proteins, growth factors, cytokines, exosomes, and extracellular vesicles. The delivery mechanism may involve deflating an air bladder to convey the atomized medication. The capsule allows for controlled transfer of the medication between chambers within it, facilitated by removing barriers and applying force.
Core Innovation
The invention provides a veterinary administration method and system in which a removable capsule includes an upper part of a vibrating mesh atomizer disposed at a lower end of and directly adjacent to a capsule chamber, so that at least one liquid formulation medication contacts the upper part of the vibrating mesh atomizer within the capsule chamber. The removable capsule is inserted into a receiving chamber of a base unit, and electrical communication between the removable capsule and the base unit supports starting the vibrating mesh atomizer.
The base unit housing defines openings for receiving portions of a resilient air bladder conduit and portions of at least one mouthpiece and a mask, and the receiving chamber is in fluid communication with a mixing chamber. Prior to administering the at least one atomized medication, a force is applied to a mask positioned over a muzzle of the animal and in fluid communication with the tubular mixing chamber, and administering is carried out using the device.
The removable capsule arrangement further includes a first chamber and a second chamber, with transfer of the liquid formulation from the first chamber to the second chamber proximate the atomizer. Stop removal and force-driven translation are used to rupture a membrane to establish fluid communication between the chambers, thereby enabling controlled movement of the medication to the region where it is atomized. The disclosed medication contents include bioactive molecules comprising proteins, lipids, and ribonucleic acid (RNA), cell-derived products, and extracellular vesicles such as exosomes.
Sensor monitoring is described for fluid parameters including viscosity, pH, particle size, pressure, and O2/CO2, and modular components are described for different patient states, including intubated and conscious scenarios. The geometry of conduits and mixing chamber features is specified, including longitudinal axes of receiving and mixing chambers arranged at an angle of forty-five degrees.
Claims Coverage
Two independent claims are present: a veterinary administration method and a system for administering medication. Across the independent claims, the coverage includes removable-capsule integration of a vibrating mesh atomizer directly adjacent to a capsule chamber, electrical contact communication to start atomization via a base unit user interface, and delivery via a mask over a muzzle and fluid communication with a tubular mixing chamber using a resilient air bladder conduit and channels/openings.
Removable vibrating mesh atomizer capsule with electrical contacts
A removable capsule having an upper part of a vibrating mesh atomizer disposed at a lower end of and directly adjacent to a capsule chamber, wherein the at least one medication contacts the upper part of the vibrating mesh atomizer within the capsule chamber; and a first electrical contact on an outward surface of the removable capsule for providing electrical communication with a base unit.
Base unit channels and mixing chamber in fluid communication for atomized medication
A base unit having a housing that defines openings for receiving portions of a conduit of a resilient air bladder and portions of at least one of a mouthpiece and a mask, with a receiving chamber in fluid communication with a mixing chamber and a second electrical contact disposed on a wall of a channel of the receiving chamber.
Mask sealing and administering atomized medication via tubular mixing chamber
Prior to administering the at least one atomized medication to the animal using the device, applying a force to a mask positioned over a muzzle of the animal and in fluid communication with the tubular mixing chamber, and administering the at least one atomized medication to the animal using the device.
User interface configured to start vibrating mesh atomizer
A base unit comprising a first channel, a chamber, and a user interface, the first channel in fluid communication with the chamber of the base unit, wherein the user interface is configured to be acted on to start the vibrating mesh atomizer to atomize the at least one medication.
The independent claims collectively cover a removable capsule that directly integrates a vibrating mesh atomizer with a capsule chamber and communicates with a base unit via electrical contacts, where the base unit includes channels and openings in fluid communication with a mixing or tubular mixing chamber and provides a user interface to start atomization. Delivery is performed using a mask over the animal’s muzzle in fluid communication with the mixing chamber while atomized medication is administered using the device.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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