Apparatus, systems and methods for transvascular access to the brain
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Publication Number
US-11931101-B2
Publication Date
2024-03-19
Expiration Date
Abstract
The present disclosure discusses a devices, systems and methods for transvascular, transvenous and/or transdural access, to the brain parenchyma, subarachnoid or subdural spaces. In some embodiments, the disclosed systems and methods may be used for local drug delivery, tissue biopsy, nanofluidic or microelectronic device/component delivery/insertion/implantation, in situ imaging, ablation of abnormal brain tissue and the like. Embodiments of the present disclosure include an access catheter system for extravascular procedures in the brain having an elongate, flexible tubular body, with at least one lumen extending axially there through between a proximal end, and a distal end. The access catheter system may include a side exit port and a distal end port. Further, the access catheter system may include a selective deflector positioned within the lumen configured to deflect a procedure catheter and permit a guide catheter.
Core Innovation
The invention provides a system for providing transvascular access to an extravascular site using an access catheter that supports transvascular access. The access catheter includes an elongate tubular body with a proximal end, a distal end, and a lumen extending between the proximal end and the distal end, with an atraumatic tip at the distal end. Within the lumen at a distal portion of the elongate tubular body, an inclined barrier is disposed with an aperture passing through it.
The access catheter further includes a side exit port in the elongate tubular body that is in communication with the lumen and is located proximally adjacent to the inclined barrier. The side exit port has a transverse dimension at a longitudinally central portion, and the aperture diameter is less than the transverse dimension. This geometry is configured so that an instrument is directed out through the side exit port while the access catheter maintains a controlled internal pathway defined by the aperture and inclined barrier.
A laterally expandable support is carried on the elongate tubular body on an opposite side from the side exit port and diametrically opposite to the side exit port. The laterally expandable support has an unexpanded state and an expanded state, and is configured to expand from the unexpanded state toward the expanded state in a first radial direction against a first side of a vessel wall. As the laterally expandable support expands, the side exit port and a portion of the elongate tubular body surrounding the side exit port are forced in a second radial direction opposite the first radial direction, positioning the side exit port and the portion against a second side of the vessel wall opposite the first side, thereby enabling extravascular access at the positioned side exit port.
Claims Coverage
The partial content provides one independent claim (clm-00001). It includes three inventive features centered on an access catheter architecture for transvascular access and positioning of a side exit port against a vessel wall.
Transvascular access with atraumatic-tipped access catheter and luminal inclined barrier aperture
An access catheter for supporting transvascular access with an elongate tubular body, an atraumatic tip at the distal end, and a lumen between the proximal end and distal end, wherein an inclined barrier within the lumen at a distal portion includes an aperture passing through the inclined barrier, the aperture having an aperture diameter.
Proximally adjacent side exit port with aperture diameter constraint
A side exit port in the elongate tubular body that is in communication with the lumen and located proximally adjacent to the inclined barrier, wherein the side exit port has a transverse dimension at a longitudinally central portion and the aperture diameter is less than the transverse dimension.
Laterally expandable support forces side exit port against opposite vessel wall side
A laterally expandable support carried on an opposite side of the elongate tubular body from the side exit port and diametrically opposite to the side exit port, configured to expand from an unexpanded state to an expanded state in a first radial direction against a first side of a vessel wall, thereby forcing the side exit port and a portion of the elongate tubular body surrounding the side exit port in a second radial direction opposite the first radial direction so the side exit port and the portion are positioned against a second side of the vessel wall opposite the first side.
Independent claim coverage centers on an access catheter architecture that combines an inclined barrier with an aperture, a proximally located side exit port having a transverse-dimension relationship to the aperture diameter, and a laterally expandable support that relocates and positions the side exit port against an opposite side of the vessel wall for transvascular extravascular access.
Stated Advantages
Documented Applications
No documented applications found
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