Treatment to improve adhesive properties of corneal implant
Inventors
Daphna, Ofer • Ferera, Nahum • Dubson, Dmitry
Assignees
Publication Number
US-11903877-B2
Publication Date
2024-02-20
Expiration Date
2038-01-08
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Abstract
A method is described of improving adhesion of an ocular implant to corneal tissue by forming an implant adhesive layer on the ocular implant, the implant adhesive layer having greater adhesive strength than a rest of the implant or by forming a corneal adhesive layer on a posterior surface of a posterior portion of the corneal tissue, the corneal adhesive layer having greater adhesive strength than a rest of the corneal tissue.
Core Innovation
The invention describes a method to improve the adhesion of an ocular implant to corneal tissue by forming an adhesive layer with greater adhesive strength either on the ocular implant or on the posterior surface of the corneal tissue. This adhesive layer is created through treatments such as laser, chemical, thermal, plasma, corona, flame, or other methods to enhance adhesion beyond the rest of the implant or cornea.
The problem addressed is the challenge of bonding an implant to corneal tissue without sutures or mechanical fasteners, requiring adhesive materials to be compatible with the ocular environment and capable of providing long-term adhesion without degrading ocular quality.
Claims Coverage
The patent includes one independent claim describing the structural features of an ocular device comprising a corneal implant with distinctive shape and surface features.
Dome-shaped corneal implant with water barrier and posterior surface features
The ocular device has a dome shape with an anterior convex surface and a posterior concave surface, includes a water barrier function, and has pockets, depressions, or protrusions on the posterior inner concave surface.
The claim covers a dome-shaped corneal implant with water barrier properties and surface features to aid positioning, made from specific polymeric or biologically compatible materials.
Stated Advantages
The increased adhesion of the adhesive layer(s) helps create a bond between the implant and corneal tissue without the need for external adhesive substances.
Documented Applications
Treatment of an over-hydrated, edematous cornea by using a hydrophobic pseudo-endothelial implant as a water barrier to enable dehydration of the cornea.
Use of the implant in place of donor implants in procedures such as DSEK (Descemet Stripping Endothelial Keratoplasty) or DMEK (Descemet Membrane Endothelial Keratoplasty) surgeries.
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