Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer
Inventors
Albert, Pradeep • Nichols, Christine • Condron, David J. • Artze, Brian • SABA, Fadi • Klein, Jesse • Vad, Vijay
Assignees
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Abstract
A method is disclosed for administering medication to conscious or unconscious patients using a device with a tubular chamber. The method involves the use of a device with a tubular chamber, wherein a liquid medication is contained within a capsule. The medication is atomized by activating an atomizer, thereby generating an atomized medication consisting of particles with a maximum diameter of four microns. The atomized medication is then dispensed into the tubular chamber. Using the device, the atomized medication is administered to the patient. In cases of unconsciousness, a resilient air bladder connected to the chamber is partially deflated, allowing air transfer into the chamber. This facilitates the administration of the atomized medication. This method enables effective medication delivery in various emergency scenarios, ensuring appropriate treatment even for unresponsive patients by providing a method of using a device with modular components.
Core Innovation
The invention relates to a capsule-based medication delivery system that provides a resilient air bladder in fluid communication with a chamber in a device, where the opening of a receiving section is covered by a cap to define a capped chamber. A capsule containing at least one medication as a liquid formulation is inserted so that the capsule is in fluid communication with the capped chamber, and an atomizer is activated to atomize the liquid formulation to generate at least one atomized medication comprising a plurality of particles.
The atomized medication is dispensed from the capsule into the capped chamber and administered to the patient by conveying the atomized medication from the capped chamber. The core arrangement includes switching between configurations by removing and re-attaching the resilient air bladder and removing the removable cap, thereby placing the resilient air bladder in fluid communication with the chamber via the opening.
The invention further includes a capsule and chamber architecture that supports controlled atomization and dispensing, including internal chamber layouts such as a capsule with first and second chambers containing a liquid formulation and an atomizer located near a distal portion of the second chamber. The capsule can include an arrangement that causes the liquid formulation to move from the first chamber to the second chamber, and a stop and membrane arrangement that can be removed or ruptured to establish fluid communication between chambers for atomization.
Claims Coverage
The document provides two independent method claims. Across these independent claims, the inventive features focus on a device with a resilient air bladder and a capped chamber for atomized liquid medication conveyed to a patient, and sequencing cap removal and resilient air bladder attachment while atomizing liquid formulation in a capsule and dispensing it into a capped chamber for patient administration.
Resilient air bladder attached to a receiving section with a capped chamber for atomized liquid medication
Providing a resilient air bladder attached to a receiving section of a device, the receiving section having an opening such that the resilient air bladder is in fluid communication with a chamber within the device; removing the resilient air bladder from the receiving section; attaching a cap to cover the opening of the receiving section, thus capping the chamber; inserting a capsule containing the at least one medication so that the capsule is in fluid communication with the capped chamber of the device, wherein the at least one medication is a liquid formulation; activating an atomizer to atomize the at least one medication to generate at least one atomized medication comprising a plurality of particles; dispensing the at least one atomized medication from the capsule into the capped chamber; and administering the at least one atomized medication to the patient by conveying the at least one atomized medication from the capped chamber.
Removing a removable cap and attaching a resilient air bladder after atomization and dispensing into the capped chamber
Inserting a capsule containing the at least one medication into a device having a chamber, such that the capsule is in fluid communication with the chamber, wherein the at least one medication is a liquid formulation and wherein the device comprises a receiving section having an opening covered by a removable cap to define a capped chamber; activating an atomizer to atomize the at least one medication to generate at least one atomized medication comprising a plurality of particles; dispensing the at least one atomized medication from the capsule in fluid communication with the capped chamber, into the capped chamber; administering the at least one atomized medication to the patient by conveying the at least one atomized medication from the capped chamber; removing the removable cap from the receiving section of the device; and attaching a resilient air bladder to the receiving section of the device such that the resilient air bladder is in fluid communication with the chamber via the opening.
Both independent claims share a core method that inserts a liquid formulation capsule into a chamber, atomizes the liquid to produce atomized medication comprising a plurality of particles, dispenses the atomized medication into a capped chamber, and administers it by conveying from the capped chamber. The independent claims differ in their sequencing and structural placement of the resilient air bladder relative to the capped receiving section, including removing and later attaching the resilient air bladder and removing the removable cap to establish fluid communication.
Stated Advantages
Documented Applications
Administering at least one atomized medication to break a patient’s blood-brain barrier.
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