Systems and methods for aspiration and monitoring

Inventors

CULBERT, BRADLEY S. • Look, David M. • Carlson, Gary

Assignees

Incuvate LLC

Abstract

A system for aspiration includes an aspiration catheter including an elongate shaft including an aspiration lumen, and an open distal end, an extension tube, the lumen of the extension tube configured to be hydraulically coupled to the aspiration lumen, a peristaltic pump configured for driving fluid through the extension tube, a compressible portion disposed between the distal end and the proximal end of the extension tube, the compressible portion configured to be coupled to the peristaltic pump, such that operation of the peristaltic pump drives fluid from the aspiration lumen from the distal end of the extension tube to the proximal end of the extension tube, and a controller configured to receive a first signal from the first sensor and configured to vary the operation of the peristaltic pump based at least in part on a first signal received from a first sensor coupled to the aspiration lumen or extension tube related to a change in the characteristic of flow.

Core Innovation

The invention relates to a catheter-based aspiration system that includes an aspiration catheter with an aspiration lumen having a proximal end and an open distal end. An injection lumen extends within the aspiration lumen and has an orifice at or near the distal end, where the orifice is configured to create one or more jets that enter into the aspiration lumen when pressurized fluid is injected through the injection lumen. The aspiration catheter is configured for placement within a blood vessel of a subject.

The system further includes an extension tube having a distal end and a proximal end, with a lumen extending therebetween, where the distal end of the extension tube is hydraulically coupled to the aspiration lumen at or adjacent the proximal end of the aspiration lumen. A peristaltic pump drives fluid through the extension tube, the peristaltic pump comprising a pump base including a pressure shoe and a rotatable head with two or more compression elements arrayed around the rotatable head. A compressible tubular portion is disposed between the distal end and proximal end of the extension tube and is coupled to the pressure shoe and rotatable head such that operation of the peristaltic pump causes the rotatable head to rotate and drive fluid from the aspiration lumen through the extension tube.

The system further includes an injection pump for pressurizing fluid through the injection lumen of the aspiration catheter, and a first sensor configured to measure a characteristic of flow through at least one of the aspiration lumen or the lumen of the extension tube. A controller receives a first signal from the first sensor and varies the operation of the peristaltic pump based at least in part on receiving the first signal, wherein the first signal relates to a change in the characteristic of flow. The injection pump is controlled by a switch.

Claims Coverage

The document includes one independent claim with multiple inventive features. The claim set provides inventive coverage for jet generation within an aspiration lumen from an injection lumen/orifice, hydraulic coupling through an extension tube to a peristaltic pump with a pressure shoe and rotatable head compression elements acting on a compressible tubular portion, and flow-characteristic sensing with controller-driven variation of peristaltic pump operation based on a signal relating to a change in flow characteristic.

The independent claim combines an aspiration catheter configured to create jets via an injection lumen orifice, hydraulic coupling through an extension tube to a peristaltic pump having a pressure shoe and compression elements operating on a compressible tubular portion, and sensor-based variation of peristaltic pump operation using a controller that responds to a measured flow characteristic change.

Stated Advantages

Documented Applications

No documented applications found