Methods and systems for automatically identifying detection parameters for an implantable medical device

Inventors

Sun, Felice • Esteller, Rosana • Lee, Adam

Assignees

Neuropace Inc

Abstract

An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.

Core Innovation

The invention provides an implantable medical-device framework in which a clinician selects a region of interest on electrographic signals in a graphical representation of a physiological signal. A computer analyzes characteristics present in the region of interest to determine, from among a plurality of different activity types, a determined activity type used to characterize the region of interest. The activity types characterize the region of interest as rhythmic activity, spiking activity, or a power change compared to a predetermined norm.

After determining the activity type, the computer automatically selects a detection tool from among a plurality of different types of detection tools based on the determined activity type. The system further analyzes the region of interest to automatically derive an initial set of operating parameters for the selected detection tool and simulates a physiological activity that the detection tool operating with the initial set of operating parameters would detect.

The invention adjusts one or more values of the parameters in the initial set of operating parameters to modify a sensitivity of the detection tool so that it detects more or less of desired ones of the characteristics. The system then generates a final set of operating parameters of the detection tool based on the adjusting, including parameterization of a half-wave detector for rhythmic and spiking activity and parameter derivation and tuning for a line-length detector for a power change.

Claims Coverage

The independent claims are directed to deriving a parameter set for a detection tool in an implantable medical device by determining an activity type from a graphical region of interest, automatically selecting a corresponding detection tool, deriving initial operating parameters, simulating detection, adjusting parameters to modify sensitivity, and generating a final parameter set. The coverage includes multiple inventive features spanning activity-type determination, detection-tool selection, initial parameter derivation, simulation, sensitivity adjustment, and final parameter generation.

The inventive features are centered on determining an activity type from a graphical region of interest, selecting a detection tool based on that activity type, deriving initial operating parameters, simulating what the detection tool would detect, and adjusting parameters to modify sensitivity before generating a final set of operating parameters.

Stated Advantages

Documented Applications