Automatic dispenser for respiratory delivery device and method

Inventors

O'Flaherty, BrendanLipman, JohannLynch, Patrick JosephFredatovich, John

Assignees

De Motu Cordis Pty Ltd

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Publication Number

US-11793951-B2

Patent

Publication Date

2023-10-24

Expiration Date


Abstract

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

Core Innovation

The invention relates to an automatic respiratory particulate dispenser for delivery of a composition to an airway of a subject. The device includes a gas inlet, a gas outlet, a composition receptacle adapted to receive a composition capsule containing the composition, and a dispersion chamber for dispensing the composition into a gas flow.

A cap removably covers the capsule and, upon removal of the cap, actuates one or more primers that pierce the composition capsule to enable subsequent delivery to the airway. The device uses one or more primers each comprising a cam follower and an associated pin or blade, and a cap comprising one or more cams located so as to engage with and displace the respective primer.

The cap comprises a cap top that is movable relative to the cap and includes one or more elongate members extending from the cap top to hold the composition capsule in place. The dispersion chamber is configured to disperse the composition into the gas flow between the gas inlet and the gas outlet, and may promote rotational movement or spinning of a composition capsule within the chamber.

An adjacent deagglomerator is positioned substantially adjacent to the dispersion chamber and connected in fluid communication with the gas inlet, gas outlet, composition receptacle, and dispersion chamber. Example structures include a vortex/dispersion chamber with ports and channels, protrusions to improve dispersion, and embodiments with single-sided operation features where gas paths are substantially sealed except for inlet and outlet.

Claims Coverage

Two independent claims are identified. Both define a device architecture for airway delivery that combines a gas inlet, a gas outlet, a composition capsule in a composition receptacle, a dispersion chamber, and a cap-driven cam/primer piercing mechanism for automatically piercing the capsule, with one claim also specifying a timing relationship between cap movement and primer displacement.

Cam-driven primer piercing upon cap removal

One or more primers each comprising a cam follower and an associated pin or blade, and a cap comprising one or more cams located so as to engage with and displace the respective primer to pierce the composition capsule upon removal of the cap.

Cap top movable capsule positioning with elongate members

The cap comprises a cap top, movable relative to the cap, having one or more elongate members extending from the cap top and adapted to hold the composition capsule in place.

Dispersion chamber for gas-flow airway delivery

In fluid communication, the device comprises a gas inlet, a gas outlet, a composition receptacle adapted to receive a composition capsule containing the composition, and a dispersion chamber.

Primer displacement timing before elongate-member movement

Initial movement of the cap away from the cap top causes displacement of the respective primer prior to the one or more elongate members being moved from their position adjacent the composition capsule.

Across the independent claims, the claim coverage centers on cam-driven primers with pins or blades that pierce the composition capsule upon cap removal, a cap structure including a movable cap top and elongate members to hold the capsule, and a dispersion chamber receiving the composition for delivery via gas inlet and gas outlet to an airway.

Stated Advantages

Documented Applications

Delivery of a composition to an airway of a subject using an automatic respiratory particulate dispenser with a gas inlet, gas outlet, a composition capsule, a dispersion chamber, and a cap-actuated piercing mechanism.

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