Methods, devices, and systems for improved oxygenation patient monitoring, mixing, and delivery

Inventors

Taube, John C.

Assignees

Vapotherm Inc

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Publication Number

US-11779720-B2

Patent

Publication Date

2023-10-10

Expiration Date


Abstract

A computer implemented method is disclosed for providing adaptive control of a gas mixture for delivery to a patient via a separate external gas blender system. The computer implemented method includes receiving first SpO2 data from a regional oximeter via a regional oximeter interface; determining first PaO2 data using a first lookup table derived from a first sigmoid shaped oxyhemoglobin dissociation curve; determining a first gas mixture value using the first PaO2 data; and transmitting first adaptive feedback control data including the first gas mixture value to the separate external gas blender system via a gas blender interface.

Core Innovation

The claims describe adaptive control of a gas mixture for delivery to a patient through a separate external gas blender system. The system operates in a first mode using regional cerebral SpO₂ data and in a second mode using systemic SpO₂ data from a pulse oximeter. In each mode, a lookup table derived from a sigmoid-shaped oxyhemoglobin dissociation curve determines PaO₂ data and a gas mixture value for transmission to the external gas blender.

The system determines the validity of regional cerebral and systemic SpO₂ data and automatically switches modes according to which data is valid. Disclosed operational features also include missing lookup-table value interpolation, weighted averaging, alarm classification and severity, alerts, smart-mode suspension, manual override, and controller-integrity checks. Because the background section is omitted in the provided content, the specific problem being solved is not explicitly described in patent.

Claims Coverage

The three independent claims are claims 1, 9, and 16, covering an adaptive-control method, a computing device, and a non-transitory computer-readable storage medium across three shared inventive features.

Adaptive control method using two oximeter modes

Claim 1 covers a computer-implemented method that receives regional cerebral SpO₂ data in a first mode and systemic SpO₂ data from a pulse oximeter in a second mode. In each mode, a respective lookup table derived from a sigmoid-shaped oxyhemoglobin dissociation curve is used to determine PaO₂ data and a gas mixture value, and adaptive feedback control data is transmitted to a separate external gas blender system. The method determines the validity of both SpO₂ inputs and automatically switches modes according to which input is valid.

Computing device configured for adaptive gas-mixture control

Claim 9 covers a computing device comprising a memory and at least one processor configured to perform the two-mode adaptive-control operation. The processor receives regional cerebral or systemic SpO₂ data, determines PaO₂ data and gas mixture values using corresponding lookup tables, transmits adaptive feedback control data to a separate external gas blender system, and automatically switches modes based on the validity of the SpO₂ data.

Computer-readable storage medium storing adaptive-control instructions

Claim 16 covers a non-transitory computer-readable storage medium storing instructions for execution by one or more processors. The instructions implement the two modes using regional cerebral and systemic SpO₂ data, determine PaO₂ data and gas mixture values using corresponding lookup tables, transmit adaptive feedback control data to a separate external gas blender system, and automatically switch modes according to input validity.

The three independent claims cover the adaptive two-mode gas-mixture control operation across method, computing device, and computer-readable medium forms. Each requires processing regional cerebral or systemic SpO₂ inputs, lookup-table determination of PaO₂ data and gas mixture values, feedback transmission to an external gas blender, and automatic mode switching based on data validity.

Stated Advantages

Not explicitly described in patent.

Documented Applications

Adaptive control of a gas mixture for delivery to a patient via a separate external gas blender system.

Regulating oxygen delivery while monitoring cerebral and systemic oxygenation, including for patients at risk of cerebral hypoxia or hyperoxia.

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