Systems and methods for performing electrophysiology (EP) signal processing
Inventors
Drakulic, Budimir S. • FAKHAR, Sina • Foxall, Thomas G. • VLAJINIC, Branislav • Asirvatham, Samuel J.
Assignees
Biosig Techonologies Inc • Mayo Clinic in Florida • Streamex Corp
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Publication Number
US-11737699-B2
Publication Date
2023-08-29
Expiration Date
Abstract
Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.
Core Innovation
The disclosed system provides a clinical electrocardiogram (ECG) and intracardiac (IC) visualization interface configured to detect a selected pattern on a surface ECG lead and, upon each detection, display corresponding ECG and intracardiac signal portions side-by-side and vertically stacked along a time axis. The interface supports configurable time interval sizing and selectable scrolling modes, including time mode and beat mode, to present a synchronized view of detected beat patterns. A review window is provided with capture configuration for presenting signal portions around detected pattern occurrences.
The interface further includes a dynamic baseline view that uses selectable trigger types to reduce off-screen drift by pinning or dynamically managing a baseline reference. A trigger view synchronizes other signals to a selected pacing-signal characteristic, with an option to pin signals for a set time after the trigger. The visualization is supported with GUI calipers configured for amplitude, time, and BPM measurement, and includes pattern matching using correlation and MAD, with confidence factors and pattern detection thresholding.
The disclosure describes an electrophysiology signal processing architecture that acquires electrocardiogram signals and intracardiac signals using dedicated hardware that includes an ECG circuit board and one or more IC circuit boards. The hardware uses a shared circuit topology and substantially same circuit/path across ECG and IC boards to support production of a clean unipolar signal, while using input protection for high-voltage applications. For high-frequency interference associated with ablation and defibrillation, the system applies RF filtering at ablation-band frequencies, together with large-signal detection and fast-recovery circuitry, dynamic notch filtering via cycle and noise buffers, and impulse-blanking high-pass filtering.
Claims Coverage
Independent claims are not explicitly described in the provided text. No independent claims are provided in the input.
Not explicitly described in patent.
Stated Advantages
Displays ECG and intracardiac signal portions side-by-side and vertically stacked along a time axis in response to detected patterns.
Provides configurable time interval sizes and selectable scrolling modes, including time mode and beat mode, for visualization.
Reduces off-screen drift via a dynamic or pinned baseline view using selectable trigger types.
Synchronizes signals using a trigger view tied to a selected pacing-signal characteristic, with optional pinning after the trigger.
Enables amplitude, time, and BPM measurements using GUI calipers.
Supports pattern matching using correlation and MAD with confidence factors and pattern detection thresholds.
Allows saving and selecting reference beats and running pattern searches with summary and detail display, including overlapping pattern highlighting and per-lead confidence visualization.
Produces a clean unipolar signal using ECG board and multiple IC boards with substantially same processing paths.
Removes saturation quickly by using large-signal detection and a fast-recovery circuit based on time constant.
Attenuates ablation-band high-frequency signals using RF filtering while aiming to preserve high input impedance for small cardiac signals.
Supports near real-time multi-signal processing and time-aligned display using packetization, per-signal queues, processing-delay equalization, and tagged display.
Reduces noise by addressing common-mode noise such as 60 Hz and 180 Hz and using dynamic notch filtering via cycle and noise buffers.
Suppresses transient artifacts while preserving high-frequency signal content using impulse-blanking high-pass filtering.
Documented Applications
Clinical ECG and intracardiac visualization and review for detecting selected beat patterns on a surface ECG lead and viewing synchronized corresponding intracardiac signal portions.
Pattern search and review workflow using reference beats, summary/detail display, overlapping pattern highlighting, and per-lead confidence visualization.
Near real-time processing and display of multiple EP signals for multi-signal review, including tagged and time-aligned display.
Visualization of late potential and early activation using described logic.
Assessment and behavior illustration of common-mode noise and in-band differential signals, and attenuation behavior for an ablation signal around 500 kHz.
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