Methods and apparatus for detecting injury using multiple types of magnetic resonance imaging data

Inventors

Murray, Christopher I. • Ross, Andrew N. • Cook, Douglas J.

Assignees

Voxel AI Inc

Abstract

Methods and apparatus for evaluating an impact of injury to brain networks or regions are provided. The method comprises receiving MRI data of a brain of an individual, including a first volumetric dataset recorded using first imaging parameters and a second volumetric dataset recorded using second imaging parameters, combining, on a voxel-by-voxel basis, first MRI data based on the first volumetric dataset and second MRI data based on the second volumetric dataset to produce a volumetric injury map, performing a structural-functional analysis of one or more brain networks or regions by refining the volumetric injury map using a volumetric eloquence map that specifies eloquent brain tissue within the one or more brain networks or regions to determine an impact of injury within the one or more brain networks or regions, and displaying a visualization of the determined impact of injury within the one or more brain networks or regions.

Core Innovation

The disclosed subject matter evaluates an impact of injury to brain networks or regions by receiving magnetic resonance imaging (MRI) data of a brain of an individual. The MRI data includes a first volumetric dataset recorded using first imaging parameters and a second volumetric dataset recorded using second imaging parameters. The approach combines the first MRI data and the second MRI data on a voxel-by-voxel basis to produce a volumetric injury map.

Structural-functional analysis is performed by refining the volumetric injury map using a volumetric eloquence map. The volumetric eloquence map specifies eloquent brain tissue within the one or more brain networks or regions. This refinement is used to determine an impact of injury within the one or more brain networks or regions, as assessed in relation to functionally relevant eloquent brain tissue.

The results of the structural-functional analysis are presented by displaying a visualization of the determined impact of injury within the one or more brain networks or regions. The system links multi-parameter MRI fusion, voxel-wise construction of a volumetric injury map, and refinement using a volumetric eloquence map to provide an injury impact output in the context of brain networks or regions.

Claims Coverage

The provided portion includes three independent claims. Across these claims, the main inventive features are consistent: receiving multi-parameter MRI volumetric datasets, producing a volumetric injury map via voxel-by-voxel combining, refining via a volumetric eloquence map for structural-functional analysis, and displaying a visualization of the determined impact of injury.

Each independent claim is directed to evaluating impact of injury to brain networks or regions by multi-parameter MRI reception, voxel-by-voxel combining into a volumetric injury map, refining that map with a volumetric eloquence map to support structural-functional analysis, and producing a visualization of the determined impact.

Stated Advantages

Documented Applications

No documented applications found