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Publication Number
US-11678840-B2
Publication Date
2023-06-20
Expiration Date
Abstract
Provided are systems, methods, and devices for providing mediation of a traumatic brain injury. Systems may include an interface, processing devices, and a controller. The interface is configured to obtain measurements from a brain of a user with a traumatic brain injury. A first processing device is configured to generate multiple brain state parameters characterizing one or more features of a brain state of the user. A second processing device is configured to generate models of the brain of the user based on the plurality of brain state parameters and the plurality of measurements, and determine, using the models and training data comprising one or more mediation data points, a mediation procedure for reducing one or more symptoms of the traumatic brain injury. The mediation procedure is provided to one or more entities, and one or more control signals are generated by the controller based on the mediation procedure.
Core Innovation
A system and method are described for closed-loop mediation of a traumatic brain injury using a brain interface to obtain a plurality of measurements from a brain of a user with a traumatic brain injury. Using a processing device, the system generates a plurality of brain state parameters characterizing one or more features of at least one brain state of the user and trains a neural network to generate one or more models of the brain of the user.
The neural network is trained using training data generated, at least in part, from one or more mediation data points, the plurality of brain state parameters, and the plurality of measurements. A procedure for mediation is determined using at least the one or more models, and the procedure for mediation is configured to reduce one or more symptoms of the traumatic brain injury.
A controller generates one or more control signals for performing an operation on the brain of the user to suppress epileptic seizures, where the control signals are generated based on the procedure for mediation. The processing and control architecture is closed-loop, using updated measurements from the interface and associated brain state parameters to drive the mediation procedure and the control signals.
Claims Coverage
The independent claims are threefold: a system claim, a method claim, and a non-transitory computer readable medium claim. Across these independent claims, there are four main inventive features: obtaining measurements via an interface, generating brain state parameters and training a neural network to generate brain models to determine a mediation procedure, determining the mediation procedure to reduce traumatic brain injury symptoms, and using the mediation procedure to generate control signals that perform an operation on the brain to suppress epileptic seizures.
Brain interface measurement acquisition for traumatic brain injury
An interface configured to obtain a plurality of measurements from a brain of a user with a traumatic brain injury.
Brain state parameters and neural network models trained using mediation data points
Generating a plurality of brain state parameters characterizing one or more features of at least one brain state of the user, and training a neural network to generate one or more models of the brain of the user, wherein the neural network is trained using training data generated, at least in part, from one or more mediation data points, the plurality of brain state parameters, and the plurality of measurements.
Procedure for mediation determined from brain models to reduce traumatic brain injury symptoms
A procedure for mediation is determined using at least the one or more models, the procedure for mediation configured to reduce one or more symptoms of the traumatic brain injury.
Control signals for brain operation to suppress epileptic seizures based on the mediation procedure
A controller generates one or more control signals for performing an operation on the brain of the user to suppress epileptic seizures, wherein the one or more control signals are generated based on the procedure for mediation.
The independent claims define a closed-loop TBI mediation architecture in which interface-based brain measurements feed processing that generates brain state parameters and trains a neural network to produce user brain models, which are used to determine a mediation procedure to reduce TBI symptoms. That mediation procedure then drives generation of control signals for an operation on the brain to suppress epileptic seizures.
Stated Advantages
Reduce one or more symptoms of the traumatic brain injury.
Suppress epileptic seizures using control signals generated based on the procedure for mediation.
Documented Applications
No documented applications found
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