Ventilation system with mechanical ventilation and extracorporeal blood gas exchange
Inventors
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Assignees
Member
Hamilton Medical Inc.Hamilton Medical is focused on the development, manufacturing, and training for advanced respiratory support technologies. The company provides intelligent ventilation systems, high flow oxygen therapy, noninvasive ventilation, and educational platforms for healthcare professionals. Their offerings emphasize patient safety, data-driven decision making, and regulatory compliance across intensive care, transport, neonatal, and emergency settings.
Hamilton Medical is focused on the development, manufacturing, and training for advanced respiratory support technologies. The company provides intelligent ventilation systems, high flow oxygen therapy, noninvasive ventilation, and educational platforms for healthcare professionals. Their offerings emphasize patient safety, data-driven decision making, and regulatory compliance across intensive care, transport, neonatal, and emergency settings.
Publication Number
US-11642445-B2
Publication Date
2023-05-09
Expiration Date
Abstract
A system for supporting the blood gas exchange by means of mechanical ventilation and extracorporeal blood gas exchange comprises a ventilation device for mechanical ventilation of the lungs of a patient, and an ECLS device for the extracorporeal blood gas exchange, wherein the ventilation system is designed to perform mechanical respiratory support by the ventilation device on the one hand and an extracorporeal blood gas exchange by the ECLS device on the other hand in coordinated, automated manner in order to support the gas exchange in the blood circulation of the patient, wherein the ECLS device sets a level of the extracorporeal blood gas exchange, and the ventilation device, on the basis of the level of the extracorporeal blood gas exchange set by the ECLS device, adjusts in automated manner to a level of the mechanical respiratory support.
Core Innovation
The invention relates to a ventilation system for supporting blood gas exchange by mechanical ventilation and extracorporeal blood gas exchange in a coordinated automated manner. The system includes a ventilation device for mechanical ventilation of lungs and an extracorporeal lung support (ECLS) device for extracorporeal blood gas exchange. A controller is coupled to the ventilation device to coordinate mechanical respiratory support and extracorporeal blood gas exchange to support gas exchange in blood of a patient.
The ECLS device is configured to adjust and set a level of the extracorporeal blood gas exchange. The controller receives the level of extracorporeal blood gas exchange set by the ECLS device and determines a maximum positive end-expiratory pressure based on the received level such that the maximum positive end-expiratory pressure fluctuates in real time in response to the level of extracorporeal blood gas exchange.
In the closed-loop control system, the controller adjusts the positive end-expiratory pressure such that the positive end-expiratory pressure does not exceed the maximum positive end-expiratory pressure. The coordinated automated approach supports a gradual shift between extracorporeal exchange and increased mechanical ventilation while preserving target oxygen and CO2 levels.
Claims Coverage
The provided material includes two independent claims. Both claims share the coordination of an ECLS device and a mechanical ventilation device using a controller, where an ECLS-set level drives a real-time, fluctuating maximum positive end-expiratory pressure (PEEP) that constrains closed-loop PEEP adjustment.
Coordinated automated mechanical ventilation and ECLS blood gas exchange
A ventilation system performs mechanical respiratory support by a ventilation device and extracorporeal blood gas exchange by an ECLS device in a coordinated automated manner to support gas exchange in blood of a patient.
ECLS-set level determines a real-time fluctuating maximum PEEP for closed-loop control
A controller receives the level of extracorporeal blood gas exchange set by the ECLS device and determines a maximum positive end-expiratory pressure based on the received level such that the maximum positive end-expiratory pressure fluctuates in real time in response to that level, and the controller adjusts positive end-expiratory pressure in a closed-loop control system so it does not exceed the maximum positive end-expiratory pressure.
ECLS oxygenation degree including blood oxygen enrichment drives the PEEP maximum
The level of extracorporeal blood gas exchange set by the ECLS device is associated with a degree of extracorporeal support in oxygenation that includes enriching the blood with oxygen, and this degree determines a maximum positive end-expiratory pressure for the closed-loop control of positive end-expiratory pressure.
Autonomous monitoring and closed-loop adjustment of ventilation parameters including PEEP
The controller autonomously monitors ventilation parameters including positive end-expiratory pressure and adjusts positive end-expiratory pressure in a closed-loop control system such that it does not exceed the maximum positive end-expiratory pressure.
Across the independent claims, the inventive focus is on coordinating automated mechanical ventilation with ECLS such that the ECLS device sets a level of extracorporeal blood gas exchange, the controller derives a real-time fluctuating maximum PEEP from that level, and a closed-loop controller autonomously adjusts PEEP without exceeding the derived maximum.
Stated Advantages
Supports gas exchange in blood of the patient in a coordinated automated manner using both mechanical respiratory support and extracorporeal blood gas exchange.
Ensures positive end-expiratory pressure does not exceed a maximum positive end-expiratory pressure determined from the ECLS-set level, by closed-loop control.
Provides a real-time fluctuating maximum positive end-expiratory pressure in response to the level of extracorporeal blood gas exchange received from the ECLS device.
Enables control of mechanical ventilation in coordination with extracorporeal support associated with oxygenation including enriching the blood with oxygen.
Documented Applications
No documented applications found
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