Uncaging stent
Inventors
Sirhan, Motasim • Yan, John • Bhat, Vinayak • Paraschac, Joseph • Cryer, Brett • Serna, Benjamyn
Assignees
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Publication Number
US-11622872-B2
Publication Date
2023-04-11
Expiration Date
Abstract
A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.
Core Innovation
The invention relates to an endoluminal prosthesis having a scaffold with a plurality of circumferential rings patterned from a non-degradable material. The scaffold is configured to expand from a crimped configuration to an expanded configuration in a physiological environment, and at least some adjacent circumferential rings comprise separation regions configured to separate after expansion.
The separation regions include attachment points where adjacent circumferential rings are joined through circumferentially separable axial links. The circumferentially separable axial links comprise a first segment and a second segment divided by an axially extending dividing line or axial joining line, and the segments are held together while the scaffold is in the crimped configuration and separate after expansion while each segment remains attached to adjacent circumferential rings.
The scaffold is configured to form one continuous loop after all circumferentially separable rings and circumferentially separable axial links have separated. The circumferentially separable rings and circumferentially separable axial links comprise a pre-formed break or gap that is joined by, covered by, or embedded in a biodegradable polymer and/or adhesive that degrades in the physiologic environment.
Claims Coverage
The consolidated excerpt includes two independent claims. Across them, the coverage centers on a non-degradable expandable scaffold of circumferential rings with separation regions that separate after expansion in a physiological/physiologic environment, while adjacent rings remain axially attached through circumferentially separable axial links. Both claims also require the scaffold to form one continuous loop after separation and require a pre-formed break or gap joined/covered/embedded in a biodegradable polymer and/or adhesive that degrades in the physiologic environment.
Non-degradable expandable scaffold with circumferential ring separation regions
A scaffold having a plurality of circumferential rings patterned from a non-degradable material, configured to expand from a crimped configuration to an expanded configuration, where at least some adjacent circumferential rings comprise separation regions configured to separate after expansion of the scaffold in a physiological environment.
Circumferentially separable axial links join adjacent rings at separation regions
At least some adjacent circumferentially separable rings are joined at attachment points at the separation regions through circumferentially separable axial links.
Segmented axial links held together in crimped configuration and circumferentially separate in expanded configuration
Circumferentially separable axial links comprise a first segment and a second segment divided by an axially extending dividing line or an axial joining line, held together while the scaffold is in the crimped configuration and configured to circumferentially separate when the scaffold is in the expanded configuration.
Post-expansion circumferential opening at separation regions while axial link segments remain attached
After expansion the segments circumferentially separate and the circumferential rings circumferentially open at the separation regions separate at the attachment points while each segment of the axial link remains attached to the attachment points on adjacent circumferential rings.
One continuous loop after separation of circumferential rings and axial links
The scaffold is configured to form one continuous loop after all circumferentially separable rings and circumferentially separable axial links have separated.
Pre-formed break or gap joined/covered/embedded in biodegradable polymer and/or adhesive
The circumferentially separable rings and circumferentially separable axial links comprise a pre-formed break or gap, wherein the preformed gap or break is joined by, covered by, or embedded in a biodegradable polymer and/or adhesive which degrades in the physiologic environment.
Divided axial joining line segments with bends, curves, or angles inhibit separation during expansion
Circumferentially separable axial links are divided along an axial joining line into two segments each having one or more corresponding bends, curves, straight areas, angles, or any combination thereof, wherein the segments are configured to be held together and inhibit separation of the segments during expansion of the scaffold, but are configured to separate along the axial joining line following expansion of the scaffold in a physiologic environment.
Across the independent claims, the inventive coverage requires an endoluminal expandable scaffold made of non-degradable circumferential rings with separation regions that separate after expansion in a physiological/physiologic environment. Circumferentially separable axial links transition from held-together segments to separated segments along an axially extending dividing line or axial joining line while maintaining axial attachment at the attachment points. After separation, the scaffold forms one continuous loop, and the architecture includes a pre-formed break or gap joined/covered/embedded in a biodegradable polymer and/or adhesive that degrades in the physiologic environment.
Stated Advantages
Allows circumferential separation and opening of circumferential rings at separation regions after expansion while the scaffold remains axially attached through the circumferentially separable axial link segments.
Configures the scaffold to form one continuous loop after all circumferentially separable rings and circumferentially separable axial links have separated.
Enables vessel uncaging.
Enables vaso-motion/vaso-dilation.
Enables potential further expansion beyond initial recoil.
Documented Applications
Endoluminal prosthesis use in a physiological/physiologic environment, including expansion from a crimped configuration to an expanded configuration with circumferential ring separation and circumferentially separable axial link separation while forming one continuous loop.
Vessel uncaging and vaso-motion/vaso-dilation in a physiologic environment.
Potential further expansion beyond initial recoil.
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