System and method for generating electromagnetic treatment protocols for the nervous system
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Publication Number
US-11559697-B2
Publication Date
2023-01-24
Expiration Date
Abstract
A system includes a communication interface for receiving information that includes data collected from an array of neural activity sensors that were placed on a patient during a session of applied stimuli. A processor is configured to analyze the received information to obtain a frequency spectrum for each sensor for a given stimulus of the applied stimuli. Neural network frequencies that correspond to an indicated impaired functionality of the nervous system of the patient are selected. For each selected frequencies, a spatial map of neural activity is generated. Each of the generated spatial maps is compared with retrieved corresponding spatial maps to identify treatment frequencies from among the selected neural network frequencies. A treatment protocol is generated for input into an electromagnetic field generator to cause the generator to apply to the patient an electromagnetic field at each identified treatment frequency.
Core Innovation
A protocol generation and treatment system stores a plurality of electrophysiological frequencies characteristic of known functionalities of human nervous systems, including electrophysiological frequencies previously known to be associated with neurological disorders, impairment or limited functionality. A sensing assembly receives electrophysiological information from a patient having neurological disorders, impairment or limited functionality at at least some of the plurality of stored electrophysiological frequencies.
An analyzer ascertains at which ones of the plurality of electrophysiological frequencies the electrophysiological information indicates the neurological disorders, impairment or limited functionality. A personalized treatment generator uses an output of the analyzer to generate a treatment for the patient including application of electromagnetic energy to the patient at at least some of those ones of the plurality of electrophysiological frequencies indicated to be associated with the neurological disorders, impairment or limited functionality.
The system further includes at least one patient monitoring sensor for monitoring the patient during the treatment. The documented protocol generation describes computing per-sensor frequency spectra from neural activity sensors during applied stimuli, selecting neural-network frequencies linked to impaired functionality, generating spatial activity maps for each selected frequency, comparing them to retrieved reference spatial maps, identifying treatment frequencies, and generating a treatment protocol to drive an electromagnetic field generator to apply electromagnetic fields at the identified frequencies.
The documented protocol can specify electromagnetic field parameters including frequency, amplitude/intensity, duration, and a delivery sequence characterized by order of application, intervals between applications, and repetition. Monitoring sensors can monitor during treatment and allow modification of amplitude and/or duration based on monitored results.
Claims Coverage
The independent claim covers an automated protocol generation and treatment system that links patient electrophysiological information to stored electrophysiological frequencies associated with neurological disorders/impairment and generates a personalized electromagnetic-energy treatment while monitoring the patient during treatment. The independent claim includes five inventive feature clusters, with additional refinements in dependent claims focused on protocol parameterization and sensing/analyzer specifics.
Database storing electrophysiological frequencies linked to nervous system functionality
A database storing a plurality of electrophysiological frequencies characteristic of known functionalities of human nervous systems, including electrophysiological frequencies previously known to be associated with neurological disorders, impairment or limited functionality.
Sensing assembly receiving patient electrophysiological information at associated frequencies
A sensing assembly for receiving electrophysiological information from a patient having neurological disorders, impairment or limited functionality at at least some of said plurality of electrophysiological frequencies stored in said database, which are previously known to be associated with said neurological disorders, impairment or limited functionality.
Analyzer ascertaining which stored frequencies indicate impairment
An analyzer ascertaining at which ones of said plurality of electrophysiological frequencies, said electrophysiological information indicates said neurological disorders, impairment or limited functionality.
Personalized treatment generator applying electromagnetic energy at indicated frequencies
A personalized treatment generator operative using an output of said analyzer for generating a treatment for said patient including application of electromagnetic energy to said patient at at least some of those ones of said plurality of electrophysiological frequencies indicated to be associated with said neurological disorders, impairment or limited functionality.
Patient monitoring sensor during electromagnetic treatment
At least one patient monitoring sensor for monitoring said patient during said treatment.
Overall coverage includes stored electrophysiological frequencies characteristic of known nervous system functionalities, patient sensing at at least some of those stored frequencies, an analyzer that ascertains which stored frequencies are indicated by the patient information, and a personalized treatment generator that applies electromagnetic energy at the indicated frequencies, with patient monitoring during treatment. Dependent refinements further specify treatment protocol parameters such as amplitude and duration and delivery scheduling characteristics including order, intervals, and periodicity, and narrow sensor modality and analyzer inputs using multiple neural activity sensors.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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