Semiconductor-sensor based near-patient diagnostic system and methods

Inventors

Mohanty, PritirajErramilli, Shyamsunder

Assignees

FemtoDx Inc

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Publication Number

US-11543380-B2

Patent

Publication Date

2023-01-03

Expiration Date


Abstract

A semiconductor sensor-based near-patient diagnostic system and related methods.

Core Innovation

The claim set focuses on generating sensor data from electrically driven nanowire sensor elements in fluid communication with a tested fluid sample using an alternating current modulated on a direct current bias. The analyte data is based on sensor data received from a sensor device in communication with a reader device and is indicative of whether an analyte is present in the fluid sample.

The analyte data is received from a reader device via a communication channel and stored in a database, where at least a portion of the analyte data is processed to generate data. The sensor element includes at least one nanowire with surface binding sites that bind charged molecules in a fluid sample, configuring the sensor element to function as a field effect transistor, and the nanowire is electrically connected to a source and a drain.

Claims Coverage

The document provides one independent computerized method claim, with additional dependent claims, centered on receiving analyte data from sensor-generated signals, storing the data in a database, and processing it. The claim set includes 9 inventive features.

Receiving analyte data generated from sensor signals via communication channel

Receiving analyte data from a reader device via a communication channel, where the analyte data is based on sensor data received from a sensor device in communication with the reader device and is indicative of whether an analyte was present in a fluid sample tested using a set of sensor elements.

Electrical driving of sensor elements in fluid communication with fluid sample

Generating the sensor data based on at least one electrical signal received from the sensor device determined by electrically driving a set of sensor elements while in fluid communication with the fluid sample.

Alternating current modulated on a direct current bias across nanowire

Electrically driving the set of sensor elements comprises applying an alternating current modulated on a direct current bias across at least one nanowire of the sensor element.

Database storing and processing to generate data

Storing the analyte data in a database and processing at least a portion of the analyte data in the database system to generate data.

Test panel for a plurality of analytes associated with a patient

Processing at least a portion of the analyte data includes performing a test panel for a plurality of analytes associated with a patient.

Wireless receiving of analyte data via communication channel

Receiving at least part of the analyte data via a wireless communication channel.

Wired receiving of analyte data from multiple reader devices

Receiving at least part of the analyte data via a wired communication channel from one or more reader device.

Nanowire sensor element with surface binding sites binding charged molecules as field effect transistor

The sensor element includes at least one nanowire with surface binding sites that bind charged molecules in a fluid sample, configuring the sensor element to function as a field effect transistor.

Nanowire electrically connected to source and drain

The sensor element includes a source and a drain, and the at least one nanowire is electrically connected to the source and the drain.

The claims cover receiving, storing, and processing analyte data from nanowire-based sensor elements driven with an alternating current modulated on a direct current bias, together with wireless and wired communication options, patient-associated test panels, and nanowire sensor structural configurations.

Stated Advantages

Documented Applications

No documented applications found

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