Monitoring computed tomography (CT) scan image
Inventors
Warier, Prashant • Modi, Ankit • Putha, Preetham • Vanapalli, Prakash • Challa, Vikash
Assignees
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Abstract
Disclosed is a system and a method for monitoring a CT scan image. A CT scan image may be resampled into a plurality of slices using a bilinear interpolation. A region of interest may be identified on each slice using an image processing technique. The region of interest may be masked on each slice using deep learning. Subsequently, a nodule may be detected as the region of interest using the deep learning. Further, a plurality of characteristics associated with the nodule may be identified. Furthermore, an emphysema may be detected in the region of interest on each slice. A malignancy risk score for the patient may be computed. A progress of the nodule may be monitored across subsequent CT scan images. Finally, a report of the patient may be generated.
Core Innovation
The invention provides a method for monitoring a Computed Tomography (CT) scan image of a patient. The method receives a CT scan image, applies gaussian smoothing to counteract noise, and resamples the CT scan image into a plurality of slices using bilinear interpolation. The method identifies a region of interest on each slice using an image processing technique and masks the region of interest by removing black or air areas and fatty tissues around the region of interest using deep learning.
Using the masked region of interest, the method detects a nodule as the region of interest with deep learning. The method determines a plurality of characteristics associated with the nodule using the image processing technique, where the plurality of characteristics comprise a diameter, a calcification, a lobulation, a spiculation, a volume, and a texture. The method also detects an emphysema in the region of interest on each slice using the deep learning.
The method computes a malignancy risk score for the patient in real-time based on the plurality of characteristics and a trained data model. The trained data model comprises historical data related to different diameter of nodules, different calcification of nodules, different lobulation of nodules, different spiculation of nodules, different volume of nodules, and different texture of nodules, and the malignancy risk score is dependent on a weightage of each characteristic. The method monitors a progress of the nodule in real-time over a predefined time period across subsequent CT scan images based on the diameter, a total volume of the nodule and the malignancy risk score, and generates a report that includes the nodule, the emphysema, the malignancy risk score, the progress of the nodule and a follow-up check with a health practitioner, thereby monitoring the CT scan image.
Claims Coverage
The independent claims cover three related aspects: a monitoring method for CT scan images, a monitoring system implementing the same workflow, and a non-transitory computer program product that stores instructions to perform the same workflow. Across these independent claims, seven inventive features are centered on deep learning-based region-of-interest masking, nodule and emphysema detection, characteristic extraction, a real-time malignancy risk score based on a trained data model with weighted characteristics, and real-time progress monitoring over a predefined time period with report generation including follow-up.
Deep learning masking of region of interest from CT slices
Identifying a region of interest on each slice using an image processing technique and masking the region of interest on each slice by removing black or air areas and fatty tissues around the region of interest using deep learning.
Deep learning nodule detection upon ROI masking
Detecting a nodule as the region of interest using the deep learning, wherein the nodule is detected upon the masking of the region of interest.
Nodule characteristic determination from image processing technique
Determining a plurality of characteristics associated with the nodule using the image processing technique, wherein the plurality of characteristics comprise a diameter, a calcification, a lobulation, a spiculation, a volume, and a texture.
Real-time emphysema detection on ROI using deep learning
Detecting an emphysema in the region of interest on each slice using the deep learning.
Real-time malignancy risk score using trained data model with weighted characteristics
Computing a malignancy risk score for the patient in real-time based on the plurality of characteristics and trained data model, wherein the trained data model comprises historical data related to different diameter of nodules, different calcification of nodules, different lobulation of nodules, different spiculation of nodules, different volume of nodules, and different texture of nodules, and wherein the malignancy risk score is dependent on a weightage of each characteristic.
Real-time nodule progress monitoring over predefined time period
Monitoring a progress of the nodule in real-time over a predefined time period across subsequent CT scan images, wherein the progress of the nodule is monitored based on the diameter, a total volume of the nodule and the malignancy risk score.
Patient report generation with follow-up check
Generating a report of the patient upon monitoring the progress of the nodule, wherein the report comprises the nodule, the emphysema, the malignancy risk score, the progress of the nodule and a follow-up check with a health practitioner, thereby monitoring the CT scan image.
The independent claims collectively cover an end-to-end CT monitoring workflow that preprocesses a CT scan image, uses deep learning to mask a region of interest and detect a nodule and emphysema, derives multiple nodule characteristics, computes a real-time malignancy risk score from a trained data model with weighted characteristics, monitors nodule progress across subsequent CT scan images over a predefined time period, and generates a patient report including follow-up with a health practitioner.
Stated Advantages
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