Operating an infusion pump system
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Publication Number
US-11471598-B2
Publication Date
2022-10-18
Expiration Date
Abstract
Some embodiments of an infusion pump system can be configured to control dispensation of medicine according to a closed-loop delivery mode that is responsive to feedback information provided from a monitoring device, and the infusion pump system permits a user to interrupt the closed-loop delivery mode for purposes of dispensing a user-selected manual bolus dosage.
Core Innovation
The invention provides an interruptible closed-loop delivery mode for a portable insulin infusion pump system, where the system automatically dispenses insulin in a closed-loop delivery mode while also detecting a trigger event from a user to initiate a user-selected manual bolus dosage. During the closed-loop delivery mode, the system calculates an effective-insulin-on-board amount for insulin dispensed during the closed-loop delivery mode by discounting previously dispensed dosage based on an amount of time since its delivery and subtracting an estimated basal rate.
The invention receives user input of an estimated number of carbohydrates to be consumed for the user-selected manual bolus dosage and calculates a calculated dosage amount for the user-selected manual bolus dosage based upon the estimated number of carbohydrates to be consumed and the calculated effective-insulin-on-board amount. The time-discounting uses a Duration Factor(t) that discounts the dosage based on an amount of time since its delivery, and the effective insulin-on-board amount is calculated as Effective Insulin-On-Board = [Σ(Dosage*Duration Factor(t))] − Estimated Basal Rate.
The invention further includes calculating an Estimated Basal Rate, including an equation of Estimated Basal Rate = Total Dose/(T*Scale Down Factor), where T is any unit of time and n is any positive whole number for the summation expression. In addition, the calculated dosage amount for a user-selected/manual bolus dosage may be determined based at least in part upon components including a suggested bolus dosage, such as a food-offsetting component and a blood glucose correction component, with the effective-insulin-on-board component subtracted from the suggested bolus dosage; the calculated dosage amount is then dispensed from the infusion pump system.
Claims Coverage
The provided independent claims are clm-00001, clm-00008, and clm-00018. They describe a portable insulin infusion pump method/system in a closed-loop delivery mode that receives user input to initiate a user-selected or user-prompted manual bolus, and they define an effective insulin-on-board calculation using a time-discounting Duration Factor(t) and an Estimated Basal Rate, followed by a carbohydrate-based bolus dosage calculation and dispensing.
User-initiated manual bolus during closed-loop delivery with dispensing
A method and/or system in which, while operating an infusion pump system to automatically dispense insulin according to a closed-loop delivery mode, a trigger event from a user initiates a user-selected manual bolus dosage, followed by calculating a calculated dosage amount and dispensing the calculated dosage amount.
Time-discounted effective insulin-on-board calculation
Calculating an effective-insulin-on-board amount calculated as Effective Insulin-On-Board = [Σ(Dosage*Duration Factor(t))] − Estimated Basal Rate, where n is any positive whole number and Duration Factor(t) discounts the dosage based on an amount of time since its delivery.
Carbohydrate input-based bolus dosage calculation
Calculating a calculated dosage amount for the user-selected/manual/user-prompted bolus dosage based upon user input of an estimated number of carbohydrates to be consumed and the calculated effective-insulin-on-board amount.
Estimated basal rate using time and scale-down factor
Calculating an Estimated Basal Rate using the formula Estimated Basal Rate = Total Dose/(T*Scale Down Factor), where T is a unit of time.
Component-based suggested bolus dosage using food offsetting and blood-glucose correction
Calculating the calculated dosage amount for the user-selected/user-prompted bolus dosage based on a suggested bolus dosage that includes a food offsetting component and a blood glucose correction component, with the effective insulin-on-board component subtracted from the suggested bolus dosage.
Across the independent claims, the core claim coverage centers on computing effective insulin-on-board using a time-discounting Duration Factor(t) and an Estimated Basal Rate, using user-provided carbohydrate information to calculate a bolus dosage, optionally decomposing the suggested bolus dosage into food-offsetting and blood-glucose correction components, and dispensing the calculated bolus while operating in a closed-loop delivery mode.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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