Container for medical liquids and method for filling a container of this type

Inventors

Härtel, Ulrich

Assignees

Vetter Pharma Fertigung GmbH and Co KG

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Publication Number

US-11446206-B2

Patent

Publication Date

2022-09-20

Expiration Date


Abstract

A container for medical liquids comprises an inner container having a distal end and a proximal end, a first porous separating element being arranged at the proximal end, the first porous separating element delimiting a holding volume for holding a medical liquid, and comprising an outer container, in which the inner container is arranged with the proximal end and with at least portions of the holding volume. The outer container extends around the inner container gas-tight such that a gas under positive pressure can be arranged in a peripheral volume arranged between an outer surface of the inner container and an inner surface of the outer container. An outlet channel section is connected to the distal end of the inner container. At least portions of the outlet channel section are arranged outside of the outer container. A valve device can be arranged in the outlet channel section, which valve device is designed, in an open position, to open a fluid connection between a distal outlet opening of the outlet channel section and the holding volume and, in a closed position, to block the fluid connection between the distal outlet opening and the holding volume.

Core Innovation

The invention relates to a stopper-free container for medical liquids. The container comprises an inner container having a distal end and a proximal end, where a first porous separating element arranged at the proximal end delimits a holding volume for holding a medical liquid.

An outer container extends around the inner container in a gas-tight manner, such that a gas under positive pressure is arranged in a peripheral volume between an outer surface of the inner container and an inner surface of the outer container. The gas transmits through the porous separating element and thereby enables injecting the medical liquid via a distal outlet opening.

A connection element for an injection device is included in an outlet channel section connected to the distal end of the inner container. A valve device arranged in the outlet channel section is operative in an open position to open a fluid connection between the distal outlet opening and the holding volume and in a closed position to block the fluid connection between the distal outlet opening and the holding volume, and the container is adapted for injecting medical liquids.

Claims Coverage

The partial content identifies one independent claim (clm-00001). It covers a stopper-free medical-liquid container combining an inner porous-separated holding volume with a surrounding gas-tight outer container carrying gas under positive pressure and a distal outlet channel with a valve that selectively connects and disconnects the holding volume to an injection device connection element.

Porous separating element delimiting a holding volume

An inner container having a distal end and a proximal end, and a first porous separating element arranged at the proximal end of the inner container, the first porous separating element delimiting a holding volume for holding a medical liquid.

Gas-tight outer container with peripheral positive-pressure gas

An outer container in which the inner container is arranged with the proximal end and with at least portions of the holding volume, the outer container extending around the inner container in a gas-tight manner, such that a gas under positive pressure is arranged in a peripheral volume between an outer surface of the inner container and an inner surface of the outer container.

Distal outlet channel connected to an injection-device connection element

An outlet channel section connected to the distal end of the inner container, the outlet channel section including a connection element for an injection device.

Outlet-channel valve selectively connecting distal outlet and holding volume

A valve device arranged in the outlet channel section, operative in an open position to open a fluid connection between a distal outlet opening of the outlet channel section and the holding volume, and in a closed position to block the fluid connection between the distal outlet opening and the holding volume.

Container adapted for injecting medical liquids

The container is adapted for injecting medical liquids.

Across the single identified independent claim, the inventive structure is defined by an inner container with a proximal porous separating element delimiting a holding volume, a gas-tight outer container holding gas under positive pressure in a peripheral volume, and a distal outlet channel section with an injection-device connection element and a valve device that selectively establishes and blocks fluid communication between the holding volume and the distal outlet opening.

Stated Advantages

Improved ergonomics and one-hand self-injection.

Defined/constant flow rate enabling precise small-volume dosing.

Reduced air bubble and air-embolism risk.

Compatibility with oxygen-sensitive medical liquids.

Avoidance of silicone lubricants.

Stable seal behavior under pressure/vacuum.

Documented Applications

Ophthalmic injections.

Multi-use injections via valve open/close cycles.

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