Compositions and methods for improving visibility of the gastrointestinal tract for endoscopy procedures
Inventors
Assignees
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Publication Number
US-11376301-B2
Publication Date
2022-07-05
Expiration Date
Abstract
Compositions and methods for improving gastrointestinal function and reducing the presence of gas bubbles in a gastrointestinal tract. A method includes administering a composition to a user during an endoscopy procedure for reducing a presence of gas bubbles in a gastrointestinal tract of a user. The composition includes an effective amount of ginger root extract for reducing the presence of the gas bubbles in the gastrointestinal tract of the user, and further includes propylene glycol and sodium chloride.
Core Innovation
The invention relates to water-soluble compositions and methods for improving visibility of a gastrointestinal tract during an endoscopy procedure by reducing a presence of gas bubbles in the gastrointestinal tract. The method includes administering a composition to a user prior to or during the endoscopy procedure. The composition comprises an effective amount of ginger root extract, propylene glycol, and sodium chloride.
In disclosed embodiments, the ginger root extract is associated with reducing gas bubbles and may be specified as including 6-gingerol and 6-shogaol. The composition may further include citric acid and ascorbic acid, along with preservatives, and water. The disclosure contrasts the disclosed composition with simethicone, which is described as effective yet not water soluble and hard to remove, and as potentially supporting biofilm and complicating cleaning/disinfection.
The disclosure further addresses endoscopy workflows in which the composition is administered during the procedure, including flushing/injecting through a colonoscope water channel and/or an auxiliary water channel, or via an instrument port. It also includes processing the colonoscope to remove composition traces for cleaning/disinfection/repurposing.
Claims Coverage
1 independent claim is identified. It covers a method for improving visibility during an endoscopy procedure by administering a specific water-soluble composition with ginger root extract and defined excipients, prior to or during the procedure.
Administering a ginger root extract composition to reduce gas bubbles during endoscopy
A method comprising administering a composition to a user prior to or during an endoscopy procedure to improve visibility of a gastrointestinal tract, wherein the composition comprises an effective amount of ginger root extract for reducing a presence of gas bubbles in the gastrointestinal tract of the user, propylene glycol, and sodium chloride.
The claim coverage centers on administering a ginger root extract-based composition with propylene glycol and sodium chloride to reduce gas bubbles during endoscopy. Dependent refinements described in the provided content further specify ginger actives (6-gingerol and 6-shogaol), optionally exclude simethicone, optionally add acids/preservatives, and narrow delivery and device-cleaning aspects.
Stated Advantages
Improves visibility of a gastrointestinal tract during an endoscopy procedure by reducing a presence of gas bubbles.
Provides a water-soluble composition as contrasted with simethicone, which is described as not water soluble and hard to remove.
Avoids simethicone, which is described as potentially supporting biofilm and complicating cleaning/disinfection.
Documented Applications
Improving gastrointestinal visibility during colonoscopy/endoscopy by reducing gas bubbles using the disclosed water-soluble ginger root extract composition administered prior to or during the procedure.
Delivering the composition during endoscopy by flushing/injecting through a colonoscope water channel and/or auxiliary water channel or via an instrument port.
Processing the colonoscope to remove composition traces for cleaning/disinfection/repurposing as part of the endoscopy workflow.
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