Systems and methods for dynamic control of enteral feeding according to energy expenditure

Inventors

Elia, Liron • Iddan, Gavriel J.

Assignees

Art Medical Ltd

Abstract

A computer-implemented method of adjusting enteral feeding of a patient by an enteral feeding controller, comprising: computing an estimate of energy expenditure of the patient based on oxygen measurements and carbon dioxide measurements of the patient, computing a target composition and target feeding rate for the enteral feeding according to the computed estimate of energy expenditure, when the target composition and target feeding rate differ from a current enteral feeding composition and feeding rate by a requirement, generating instructions for adjustment, by an enteral feeding controller, of the rate of delivery of the enteral feeding according to the target composition, wherein the receiving the oxygen measurement, receiving the carbon dioxide measurement, and computing the estimate of energy expenditure are performing iteratively for every first time interval, and the generating instructions for adjustment are performed for a second time interval that is larger than the first time interval.

Core Innovation

The invention provides a computer-implemented method and related computing device and computer program product for adjusting enteral feeding of a patient by an enteral feeding controller. The method receives signals of at least one of a carbon dioxide sensor and an oxygen sensor sensing inspiration and expiration, and receives output of a flow sensor sensing inspiration and expiration. Using the sensor outputs, the method computes energy expenditure of the patient.

The method computes a target nutritional goal for the enteral feeding that provides 100% or near 100% of the computed energy expenditure of the patient irrespective of a predictive equation. The target nutritional goal comprises caloric requirements and a target amount of protein.

The method selects a feeding formulation that provides the caloric requirements and provides less than a full amount of the target amount of protein, and selects a supplemental protein formulation that, when added to the feeding formulation, provides the full amount of the target amount of protein. The method generates instructions for adjustment by the enteral feeding controller for delivery of the feeding formulation and the supplemental protein formulation via an enteral feeding tube according to at least one of a feeding rate and a feeding composition defined by the generated instructions.

Claims Coverage

The independent claims are directed to a computer-implemented method, a computing device, and a computer program product for adjusting enteral feeding based on sensor-derived energy expenditure and a protein-supplementation approach. Across the independent claims, the inventive features are consistent in the following countable elements: sensor signal receipt, energy expenditure computation, a target nutritional goal matching computed energy expenditure without reliance on a predictive equation, caloric and protein targeting, selection of a base feeding formulation with incomplete protein, selection of a supplemental protein formulation to complete protein, and generating and providing instructions to an enteral feeding controller for delivery via an enteral feeding tube.

The independent claims cover adjusting enteral feeding by computing patient energy expenditure from carbon dioxide and/or oxygen sensor signals and flow-sensor output, then computing a target nutritional goal that matches 100% or near 100% of the computed energy expenditure without a predictive equation. The claims further require selecting a base feeding formulation that covers caloric requirements with less than the full target protein, selecting a supplemental protein formulation that completes the target protein, and generating and providing controller instructions for delivering both formulations through an enteral feeding tube according to at least one of a feeding rate and a feeding composition.

Stated Advantages

Documented Applications