Systems, devices and methods for draining and analyzing bodily fluids
Inventors
BURNETT, Daniel R. • Keenan, Rich • Sokolov, Dimitri • Boyd, Stephen • Williams, Martin • VENKATESWARA-RAO, Kondapavulur • Arney, Michelle
Assignees
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Publication Number
US-11357951-B2
Publication Date
2022-06-14
Expiration Date
Abstract
Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller. The venting mechanism may further include a valve which is configured to maintain a closed position, as well as a vent in fluid communication with the valve, where the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen.
Core Innovation
The invention relates to medical systems including a modified drainage assembly configured to prevent negative pressure build-up. The assembly includes an elongate catheter with at least one opening near or at the first end in fluid communication with a catheter lumen, and a drainage tube having a drainage lumen in fluid communication with a second end of the catheter. A rigid cassette configured to fit into a cassette mount is in fluid communication with the drainage lumen, with a drainage valve located at an entry point where the drainage lumen connects to the cassette.
The drainage assembly further includes a venting mechanism in fluid communication with the drainage lumen, and a second valve positioned within the venting mechanism. The second valve is configured to maintain a closed position until a first pressure level within the drainage lumen drops to a second pressure level, at which point the second valve moves to an open position. The vent is configured to inhibit wetting of the vent from fluid within the drainage lumen, and the controller is in communication with the cassette to determine a fluid volume collected within the cassette.
In additional aspects, the controller can determine the fluid volume collected within the cassette using pressure sensing and/or ultrasound sensing, and the system supports preventing negative pressure build-up while enabling high-fidelity physiological monitoring. The system extends sensing beyond pressure by measuring urine-related parameters and detecting conditions using multivariate parameter fingerprints and trending based on sensed parameters. The documented system also includes infection detection using UV/light/Raman spectroscopy with identified spectroscopic signatures, and supports condition detection/risk scoring for AKI/UTI/sepsis/ARDS based on the multivariate fingerprints and trending.
Claims Coverage
The partial content provides two independent claims (clm-00001 and clm-00025). Across these independent claims, the main inventive features are centered on venting with a wetting-inhibiting vent and a pressure-triggered second valve to prevent negative pressure build-up and airlock-related obstruction, and controller-based determination of collected fluid volume, with clm-00025 adding controller-applied negative pressure to transition the second valve from closed to open based on pressure-level thresholds.
Pressure-triggered wetting-inhibited venting to prevent negative pressure build-up
A drainage assembly includes an elongate catheter with a drainage lumen connected to a rigid cassette via a drainage valve, a venting mechanism in fluid communication with the drainage lumen, a second valve positioned within the venting mechanism configured to maintain a closed position until a first pressure level within the drainage lumen drops to a second pressure level such that the second valve moves to an open position, and a vent positioned in fluid communication with the second valve, wherein the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen.
Controller-determined fluid volume collected within the cassette
A drainage assembly further includes a controller in communication with the cassette, wherein the controller is configured to determine a fluid volume collected within the cassette.
Controller-applied negative pressure to open the second valve based on pressure-level thresholds
A drainage assembly includes a second valve configurable between a closed position and an open position, wherein the controller is configured to apply a negative pressure to the drainage lumen such that the second valve moves from the closed position to the open position when a first pressure level imparted upon the second valve is dropped by the controller to a second pressure level.
Together, the independent claims define a drainage assembly that prevents negative pressure build-up using a venting mechanism with a second valve that opens based on pressure-level transitions and a vent configured to inhibit wetting. Both independent claims also require controller determination of fluid volume collected within the rigid cassette, with the second independent claim further requiring the controller to apply negative pressure to drive the second valve from closed to open based on pressure-level thresholds.
Stated Advantages
Prevents negative pressure build-up.
Documented Applications
Medical systems for automated, high-fidelity physiological monitoring that enable urine drainage with negative-pressure build-up prevention.
Infection detection using UV/light/Raman spectroscopy with identified spectroscopic signatures.
Condition detection/risk scoring including AKI, UTI, sepsis, and ARDS using multivariate parameter fingerprints and trending.
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