Target site selection, entry and update with automatic remote image annotation

Inventors

Wong Po Foo, CherylSanderson, DavidAltman, Peter

Assignees

Biocardia Inc

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Publication Number

US-11357463-B2

Patent

Publication Date

2022-06-14

Expiration Date


Abstract

Fluoroscopic imaging of a patient's heart is performed by positioning a patient in a sterile field and imaging the heart using a x-ray fluoroscopy system within the sterile to produce a two-dimensional image. The two-dimensional image is simultaneously displayed on an operative display within or adjacent the sterile filed and on a display of a remote image processor outside the operative field. The two-dimensional image of the remote display is manually marked or annotated to show anatomical or treatment information which is simultaneously shown on the operative display.

Core Innovation

The invention addresses fluoroscopic imaging of a patient's heart by using an imaging modality capable of three-dimensional (3D) visualization to obtain a 3D image of the patient's heart. The heart is imaged using an x-ray fluoroscopy system in a sterile operative field to produce two orthogonal two-dimensional images, and the two-dimensional images are simultaneously displayed on both an operative display within or adjacent the sterile operative field and on a remote display of an image processor outside the sterile operative field.

A portion of the 3D image is superimposed on the two-dimensional images on the remote display. The superimposed image is marked to show anatomical information, including wall thickness and at least one myocardial infarct location of the patient's heart, and is further marked to show treatment information by marking target treatment regions of the patient's heart suitable for delivery of a biotherapeutic.

The marked superimposed image is simultaneously displayed on both the operative display and the remote display, showing both the anatomical information and the treatment information. The biotherapeutic is delivered to one or more of the target treatment regions to treat the one or more target treatment regions. The disclosure further describes multi-modality fusion using pre-operative 3D reconstructions from cardiac MRI, CT, and echocardiography, registered to orthogonal ventriculograms and projected onto live fluoroscopy.

Claims Coverage

The disclosed independent claim covers one method using 3D visualization with two orthogonal x-ray fluoroscopy views, simultaneous operative and remote display, superimposed anatomical and treatment information, and delivery of a biotherapeutic to marked target treatment regions. Four inventive features are identified.

3D visualization overlaid onto orthogonal fluoroscopy views in sterile and remote displays

Using an imaging modality capable of three-dimensional (3D) visualization to obtain a 3D image of the patient's heart, imaging the heart using an x-ray fluoroscopy system in a sterile operative field to produce two orthogonal two-dimensional images, simultaneously displaying the two-dimensional images on both an operative display and on a remote display, and superimposing at least a portion of the 3D image on the two-dimensional images on the remote display.

Remote marking of anatomy and treatment regions on superimposed image

Marking the superimposed image to show anatomical information including wall thickness and at least one myocardial infarct location, and marking the superimposed image to show treatment information by marking target treatment regions suitable for delivery of a biotherapeutic.

Simultaneous operative and remote display of marked superimposed image

Simultaneously displaying, on both the operative display and the remote display, the marked superimposed image showing both the anatomical information and the treatment information.

Delivery of biotherapeutic to marked target treatment regions

Delivering the biotherapeutic to one or more of the target treatment regions to treat the one or more target treatment regions.

The claim set centers on fusing a 3D visualization image with two orthogonal x-ray fluoroscopy images, simultaneously presenting the fused and marked anatomical and treatment information locally in a sterile field and remotely, and enabling delivery of a biotherapeutic to the marked target treatment regions.

Stated Advantages

Not explicitly described in patent.

Documented Applications

Not explicitly described in patent.

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